Entry
Name
N4-(beta-N-acetylglucosaminyl)-L-asparaginase;
aspartylglucosylamine deaspartylase;
aspartylglucosylaminase;
aspartylglucosaminidase;
aspartylglycosylamine amidohydrolase;
N-aspartyl-beta-glucosaminidase;
glucosylamidase;
beta-aspartylglucosylamine amidohydrolase;
4-N-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine amidohydrolase
Reaction(IUBMB)
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O = N-acetyl-beta-D-glucosaminylamine + L-aspartate [RN:
R03421 ]
Reaction(KEGG)
Substrate
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine [CPD:
C04540 ];
H2O [CPD:
C00001 ]
Product
N-acetyl-beta-D-glucosaminylamine [CPD:
C01239 ];
L-aspartate [CPD:
C00049 ]
Comment
Acts only on asparagine-oligosaccharides containing one amino acid, i.e., the asparagine has free alpha-amino and alpha-carboxyl groups [cf. EC
3.5.1.52 , peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase]
History
EC 3.5.1.26 created 1972 (EC 3.5.1.37 created 1972, incorporated 1976)
Pathway
Orthology
K01444 N4-(beta-N-acetylglucosaminyl)-L-asparaginase
Genes
ODA : 120860538 120865842(AGA)
MDO : 100017534(AGA) 103099919
GAS : 123233356 123251353(AGA)
PCW : 110207549 110215973(AGA)
TVP : 118841128 118854365(AGA)
ASN : 102378205 102380183(AGA)
AMJ : 102565336(AGA) 102575296
CPOO : 109309774(AGA) 109319539
GGN : 109296937 109300928(AGA)
ACS : 100565704(aga) 103279484
ASAO : 132776717(AGA) 132780641
PVT : 110083560(AGA) 110086035
SUND : 121920671 121931473(AGA)
VKO : 123023779(AGA) 123035701
PMUA : 114593570 114604378(AGA)
PRAF : 128409915 128420835(AGA)
ZVI : 118082571 118083557(AGA)
HCG : 128328221(AGA) 128339891
EMC : 129333528 129336863(AGA)
XLA : 108704291 496249(aga.L)
GSH : 117351867 117359716(AGA)
DRE : 566517(aga) 767799(zgc:153169)
SRX : 107723789 107725444 107740122
SANH : 107666437 107669106(aga)
CAUA : 113056998 113114143(aga)
CGIB : 127970378(zgc:153169) 127971929
PTET : 122356199(zgc:153169) 122357173(aga)
LROH : 127175005(zgc:153169) 127176347(aga)
OMC : 131552163(zgc:153169) 131552908(aga)
PPRM : 120474319(aga) 120480003(zgc:153169)
RKG : 130089675(zgc:153169) 130095164(aga)
MAMB : 125258739(aga) 125276888(zgc:153169)
CIDE : 127494525 127525496(zgc:153169)
CERY : 137020055(zgc:153169) 137021453(aga) 137024336
MASI : 127414136 127418199
TROS : 130558905(zgc:153169) 130564226(aga)
TDW : 130431219(zgc:153169) 130438426(aga)
MANU : 129415852(zgc:153169) 129422011(aga)
IPU : 100528085(aga) 108263419(zgc:153169)
IFU : 128605825(zgc:153169) 128612094(aga)
PHYP : 113524438(aga) 113541093
SMEO : 124386429(aga) 124400135(zgc:153169)
TFD : 113655020(aga) 113661062(zgc:153169)
TVC : 132846719(zgc:153169) 132856191(aga)
TRN : 134314281(zgc:153169) 134318929(aga)
AMEX : 103033819(zgc:153169) 103034994(aga)
CMAO : 118803224 118807299(aga) 118810695(zgc:153169)
EEE : 113579936(aga) 113582046
CHAR : 105906172(aga) 122130975(zgc:153169)
PPRL : 129360689 129360695
STRU : 115153141 115170787(aga)
OTW : 112221049(aga) 112253772(zgc:153169)
OMY : 110488927(aga) 110502391(zgc:153169)
OGO : 123993501(aga) 124038207(zgc:153169)
ONE : 115113278 115130806(aga)
OKI : 109864842(aga) 109899087
OKE : 118379535(aga) 118400878(zgc:153169)
SALP : 111965831(aga) 111977418
SNH : 120045616(zgc:153169) 120048036(aga)
CCLU : 121541517(aga) 121569839(zgc:153169)
ELS : 105005758 105027612(aga)
SFM : 108925954(aga) 108927096
PKI : 111845368(aga) 111858552
LOC : 102689588(aga) 102695882
PSPA : 121297384(aga) 121316121(zgc:153169)
ARUT : 117402935(zgc:153169) 117409427 117420464
PSEX : 120516719(zgc:153169) 120527543(aga)
LCM : 102349860(AGA) 102352273
RTP : 109920873(zgc:153169) 109925568 109930049
CPLA : 122553125(zgc:153169) 122557309 122557314
HOC : 132819907(zgc:153169) 132821334 132826880
LERI : 129716206 129716207
BBEL : 109467826 109482592
SCLV : 120329590 120332985
LPIC : 129260176 129261362
SKO : 100372230 100375807 100377602 102801911
DME : Dmel_CG10474(CG10474) Dmel_CG1827(CG1827) Dmel_CG4372(CG4372)
DSI : Dsimw501_GD10667(Dsim_GD10667) Dsimw501_GD25160(Dsim_GD25160) Dsimw501_GD25331(Dsim_GD25331)
DYA : Dyak_GE12034 Dyak_GE13669 Dyak_GE19290
DSR : 110177820 110188424 110191811
DMN : 108158225 108158805 117192974
DWI : 26529740 6641006 6641007
AALB : 109410731 115269255
CQU : CpipJ_CPIJ008337 CpipJ_CPIJ012618 CpipJ_CPIJ015646
BCOO : 119077077 119083695
CSOL : 105364943 105364944
TPRE : 106659987 106659988
LHT : 122498143 122501083 122507940
CFEL : 113369755 113369935
BTAB : 109039325 109042481
TPAL : 117644395 117644779
CEL : CELE_R04B3.2(R04B3.2)
HRO : HELRODRAFT_155397 HELRODRAFT_79843
LGI : LOTGIDRAFT_218839 LOTGIDRAFT_235285
PVUL : 126818806 126829943
PCAN : 112553697 112560366
GAE : 121376064 121380850 121391845
CRG : 105320929 105336257 105348462
CANU : 128157510 128175957 128192598
CVN : 111123509 111127014 111127257 111129917
OED : 125652840 125679336 125681499
PMAX : 117328699 117334164
MCAF : 127714218 127714219 127716694 127734129
MMER : 123556959 123556960 123558012
RPHI : 132715363 132734078 132734080
DPOL : 127858681 127876514 127880030
MAEA : 128225889 128229038
LAK : 106168421 106173810 106174761
LLON : 135493421 135493622
NVE : 5498746 5506829 5509947 5521881
ATEN : 116289987 116300268 116300269
AMIL : 114953900 114967074
PDAM : 113671622 113680388
SPIS : 111326091 111339694
CSAT : 104738920 104762269
PVY : 116139687 116140496 116140504
SHIS : 125203787 125209895
TAES : 123046410 123054252 123190139
MFLO : 136491262 136493400 136497884
PVIR : 120642683 120681779
SMO : SELMODRAFT_108968 SELMODRAFT_93118
NTE : NEUTE1DRAFT46478(NEUTE1DRAFT_46478)
SMP : 10806832(SMAC4_06038)
TATV : 25781440(TrAtP1_002811)
TASP : 36612468(TrAFT101_006571)
MAW : 19252853(J3458_000282)
PLJ : 28886340(PLICBS_007819)
GTT : GUITHDRAFT_162876 GUITHDRAFT_77590
XPH : XppCFBP6546_03060(XppCFBP6546P_03060)
SPHC : CVN68_09245 CVN68_12625
PAQI : KW060_04875 KW060_07335
FGI : OP10G_0534 OP10G_1068
NPY : NPRO_04320 NPRO_06880
PLH : VT85_03725 VT85_03745
AGV : OJF2_06320 OJF2_16930
PSPC : Strain318_000284 Strain318_001932
PSEG : D3H65_02865 D3H65_32580
FOK : KK2020170_03240(aspG)
» show all
Taxonomy
Reference
Authors
Kono M, Yamashina I.
Title
Purification and properties of 4-L-aspartylglycosylamine amidohydrolase from hog kidney.
Journal
Reference
Authors
Mahadevan S, Tappel AL.
Title
Beta-aspartylglucosylamine amido hydrolase of rat liver and kidney.
Journal
J Biol Chem 242:4568-76 (1967)
Reference
Authors
Tarentino AL, Maley F.
Title
The purification and properties of a beta-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.26
ExPASy - ENZYME nomenclature database: 3.5.1.26
LinkDB
All DBs