KEGG   ENZYME: 5.4.99.55
Entry
EC 5.4.99.55                Enzyme                                 
Name
delta-amyrin synthase;
SlTTS2 (gene name)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, delta-amyrin-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = delta-amyrin [RN:R09915]
Reaction(KEGG)
R09915
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
delta-amyrin [CPD:C20194]
Comment
The enzyme from tomato (Solanum lycopersicum) gives 48% delta-amyrin, 18% alpha-amyrin, 13% beta-amyrin and traces of three or four other triterpenoid alcohols [1]. See also EC 5.4.99.40, alpha-amyrin synthase and EC 5.4.99.39, beta-amyrin synthase.
History
EC 5.4.99.55 created 2011
Orthology
K21928  delta/alpha/beta-amyrin synthase
Genes
SLY: 100529100(TTS2)
SOT: 102591877
SSTN: 125852109
Reference
1  [PMID:21059824]
  Authors
Wang Z, Guhling O, Yao R, Li F, Yeats TH, Rose JK, Jetter R
  Title
Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids.
  Journal
Plant Physiol 155:540-52 (2011)
DOI:10.1104/pp.110.162883
  Sequence
[sly:100529100]
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.55
IUBMB Enzyme Nomenclature: 5.4.99.55
ExPASy - ENZYME nomenclature database: 5.4.99.55
BRENDA, the Enzyme Database: 5.4.99.55
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