KEGG   DRUG: Eptacog alfa
Entry
D00172                      Drug                                   
Name
Eptacog alfa (INN);
Eptacog alfa (activated) (genetical recombination) (JAN);
Coagulation Factor VIIa;
Coagulation factor VIIa (recombinant)-jncw;
Novo- seven (TN);
Sevenfact (TN)
Product
SEVENFACT (Laboratoire Français du Fractionnement et des Biotechnologies Société Anonyme (LFB S.A.))
Formula
C1982H3054N560O618S28
Exact mass
45483.6943
Mol weight
45512.72
Class
Blood modifier agent
 DG02016  Hemostatics
  DG02014  Blood coagulation accelerant
   DG02013  Blood coagulation factor
Remark
Same as: C03378
Therapeutic category: 6343
ATC code: B02BD05 B02BD08
Chemical structure group: DG00172
Product (DG00172): D00172<JP/US>
Efficacy
Bleeding suppressant, Replenisher (coagulation factor)
Comment
human FVIIa [HSA:2155] [KO:K01320] analog
See F3 [HSA:2152] [KO:K03901]
See F10 [HSA:2159] [KO:K01314]
Target
F7a [CPD:C03378] [HSA:2155] [KO:K01320]
  Pathway
hsa04610  Complement and coagulation cascades
  Network
nt06514  Coagulation cascade
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD05 Coagulation factor VII
      D00172  Eptacog alfa (INN) <JP/US>
     B02BD08 Coagulation factor VIIa
      D00172  Eptacog alfa (INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   634  Human blood preparations
    6343  Plasma preparations
     D00172  Eptacog alfa (INN); Eptacog alfa (activated) (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00172  Blood coagulation factor VII
      D00172  Eptacog alfa
Target-based classification of drugs [BR:br08310]
 Peptidases and inhibitors
  Serine peptidases
   Chymotrypsin family
    F7a
     D00172  Eptacog alfa (INN) <JP/US>
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D00172
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00172
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00172
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00172
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00172  Blood coagulation factor VII
Drug name stems [br08333.html]
 DG00172
Other DBs
CAS: 102786-61-8
PubChem: 7847240
ChEBI: 3777
LinkDB

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KEGG   DRUG: Freeze-dried activated human blood coagulation factor VII concentrate containing factor X
Entry
D12421            Mixture   Drug                                   
Name
Freeze-dried activated human blood coagulation factor VII concentrate containing factor X;
Byclot (TN)
Component
Activated human blood coagulation factor VII, Human blood coagulation factor X
Remark
Therapeutic category: 6343
ATC code: B02BD03
Product: D12421<JP>
Efficacy
Bleeding suppressant, Replenisher (coagulation factor)
Target
F10 [HSA:2159] [KO:K01314]
F7a [CPD:C03378] [HSA:2155] [KO:K01320]
  Pathway
hsa04610  Complement and coagulation cascades
  Network
nt06514  Coagulation cascade
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD03 Factor VIII inhibitor bypassing activity
      D12421  Freeze-dried activated human blood coagulation factor VII concentrate containing factor X <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   634  Human blood preparations
    6343  Plasma preparations
     D12421  Freeze-dried activated human blood coagulation factor VII concentrate containing factor X
Target-based classification of drugs [BR:br08310]
 Peptidases and inhibitors
  Serine peptidases
   Chymotrypsin family
    F7a
     D12421  Freeze-dried activated human blood coagulation factor VII concentrate containing factor X <JP>
    F10
     D12421  Freeze-dried activated human blood coagulation factor VII concentrate containing factor X <JP>
Other DBs
PubChem: 497620834
LinkDB

» Japanese version   » Back

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