KEGG   Homo sapiens (human): 2152
Entry
2152              CDS       T01001                                 
Symbol
F3, CD142, TF, TFA
Name
(RefSeq) coagulation factor III, tissue factor
  KO
K03901  coagulation factor III (tissue factor)
Organism
hsa  Homo sapiens (human)
Pathway
hsa04610  Complement and coagulation cascades
hsa04933  AGE-RAGE signaling pathway in diabetic complications
Network
nt06514  Coagulation cascade
  Element
N01503  Extrinsic pathway of coagulation cascade, F7 activation
N01510  Common pathway of coagulation cascade, F10 activation
Drug target
Tifacogin: D06142
Tisotumab: D11813
Tisotumab vedotin: D11814<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    2152 (F3)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    2152 (F3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    2152 (F3)
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
    2152 (F3)
CD molecules [BR:hsa04090]
 Proteins
  2152 (F3)
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:hsa00537]
 Others
  2152 (F3)
SSDB
Motif
Pfam: Tissue_fac Interfer-bind KIAA1549 Baculo_11_kDa
Other DBs
NCBI-GeneID: 2152
NCBI-ProteinID: NP_001984
OMIM: 134390
HGNC: 3541
Ensembl: ENSG00000117525
Pharos: P13726(Tchem)
UniProt: P13726
Structure
LinkDB
Position
1:complement(94529173..94541759)
AA seq 295 aa
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPK
PVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGS
AGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFG
KDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVE
CMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
NT seq 888 nt   +upstreamnt  +downstreamnt
atggagacccctgcctggccccgggtcccgcgccccgagaccgccgtcgctcggacgctc
ctgctcggctgggtcttcgcccaggtggccggcgcttcaggcactacaaatactgtggca
gcatataatttaacttggaaatcaactaatttcaagacaattttggagtgggaacccaaa
cccgtcaatcaagtctacactgttcaaataagcactaagtcaggagattggaaaagcaaa
tgcttttacacaacagacacagagtgtgacctcaccgacgagattgtgaaggatgtgaag
cagacgtacttggcacgggtcttctcctacccggcagggaatgtggagagcaccggttct
gctggggagcctctgtatgagaactccccagagttcacaccttacctggagacaaacctc
ggacagccaacaattcagagttttgaacaggtgggaacaaaagtgaatgtgaccgtagaa
gatgaacggactttagtcagaaggaacaacactttcctaagcctccgggatgtttttggc
aaggacttaatttatacactttattattggaaatcttcaagttcaggaaagaaaacagcc
aaaacaaacactaatgagtttttgattgatgtggataaaggagaaaactactgtttcagt
gttcaagcagtgattccctcccgaacagttaaccggaagagtacagacagcccggtagag
tgtatgggccaggagaaaggggaattcagagaaatattctacatcattggagctgtggta
tttgtggtcatcatccttgtcatcatcctggctatatctctacacaagtgtagaaaggca
ggagtggggcagagctggaaggagaactccccactgaatgtttcataa

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