KEGG   DRUG: TrimipramineHelp
Entry
D00394                      Drug                                   

Name
Trimipramine (USAN/INN)
Formula
C20H26N2
Exact mass
294.2096
Mol weight
294.4338
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01730  Non-selective monoamine reuptake inhibitor
 DG01728  Tricyclic antidepressant
Remark
ATC code: N06AA06
Chemical structure group: DG00931
Product (DG00931): D02408<JP/US>
Efficacy
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI)
Target
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A4 (HTT) [HSA:6532] [KO:K05037]
  Pathway
hsa04726  Serotonergic synapse
Interaction
Drug interaction
Structure map
map07027  Antidepressants
map07234  Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AA Non-selective monoamine reuptake inhibitors
     N06AA06 Trimipramine
      D00394  Trimipramine (USAN/INN)
USP drug classification [BR:br08302]
 Antidepressants
  Tricyclics
   Trimipramine
    D00394  Trimipramine (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D00394  Trimipramine (USAN/INN)
    SLC6A4 (HTT)
     D00394  Trimipramine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 739-71-9
PubChem: 7847460
ChEBI: 9738
ChEMBL: CHEMBL644
DrugBank: DB00726
LigandBox: D00394
NIKKAJI: J6.960D
LinkDB All DBs
KCF data Show

ATOM        22
            1   C1x C    30.5200  -20.7200
            2   C8y C    29.6800  -19.6000
            3   C8y C    30.0300  -18.2700
            4   N1y N    31.2900  -17.7100
            5   C1x C    31.9200  -20.7200
            6   C8y C    32.5500  -18.3400
            7   C8y C    32.8300  -19.6700
            8   C8x C    28.9800  -17.2900
            9   C8x C    27.5800  -17.7100
            10  C8x C    27.2300  -19.0400
            11  C8x C    28.3500  -20.0200
            12  C8x C    34.1600  -20.0900
            13  C8x C    35.2100  -19.1800
            14  C8x C    34.9300  -17.7800
            15  C8x C    33.6000  -17.3600
            16  C1b C    31.2900  -16.3100
            17  C1c C    32.4800  -15.6100
            18  C1b C    33.6700  -16.3100
            19  C1a C    32.4800  -14.2100
            20  N1c N    34.8600  -15.6100
            21  C1a C    36.0500  -16.3100
            22  C1a C    34.8600  -14.2100
BOND        24
            1     3   4 1
            2     1   5 1
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    7  12 2
            14   12  13 1
            15   13  14 2
            16   14  15 1
            17    6  15 2
            18    4  16 1
            19   16  17 1
            20   17  18 1
            21   17  19 1
            22   18  20 1
            23   20  21 1
            24   20  22 1

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