KEGG   DRUG: OxybutyninHelp
Entry
D00465                      Drug                                   

Name
Oxybutynin (USAN/INN);
Anturol (TN);
Oxytrol (TN)
Product
Formula
C22H31NO3
Exact mass
357.2304
Mol weight
357.4864
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01491  Muscarinic cholinergic receptor antagonist
Metabolizing enzyme substrate
 DG02913  CYP3A4 substrate
 DG02925  CYP3A5 substrate
Remark
Same as: C07360
ATC code: G04BD04
Chemical structure group: DG00478
Product (DG00478): D00465<US> D00722<JP/US>
Efficacy
Antipollakisuria, Overactive bladder agent, Muscarinic acetylcholine receptor antagonist
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
Metabolism
Enzyme: CYP3A4 [HSA:1576], CYP3A5 [HSA:1577]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BD Urinary antispasmodics
     G04BD04 Oxybutynin
      D00465  Oxybutynin (USAN/INN) <US>
USP drug classification [BR:br08302]
 Genitourinary Agents
  Antispasmodics, Urinary
   Oxybutynin
    D00465  Oxybutynin (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    CHRM
     D00465  Oxybutynin (USAN/INN) <US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00465
Rx-to-OTC switch list in the USA [br08315.html]
 D00465
BRITE hierarchy
Other DBs
CAS: 5633-20-5
PubChem: 7847531
ChEBI: 7856
ChEMBL: CHEMBL1231
DrugBank: DB01062
LigandBox: D00465
NIKKAJI: J8.038A
LinkDB All DBs
KCF data Show

ATOM        26
            1   C3b C    14.7700  -23.0300
            2   C1b C    15.9824  -23.7300
            3   O7a O    17.1949  -23.0300
            4   C7a C    18.4073  -23.7300
            5   C1d C    19.6197  -23.0300
            6   C8y C    20.8322  -23.7300
            7   C8x C    22.0446  -23.0300
            8   C8x C    23.2570  -23.7300
            9   C8x C    20.8322  -25.1300
            10  C8x C    22.0446  -25.8300
            11  C8x C    23.2570  -25.1300
            12  C1y C    19.6197  -21.6300
            13  C1x C    20.8173  -20.9385
            14  C1x C    20.8172  -19.5385
            15  C1x C    19.6047  -18.8386
            16  C1x C    18.4071  -19.5301
            17  C1x C    18.4072  -20.9301
            18  O1a O    20.8322  -22.3300
            19  O6a O    18.4073  -25.1300
            20  C3b C    13.5576  -22.3300
            21  C1b C    12.3451  -21.6300
            22  N1c N    11.1140  -22.3410
            23  C1b C     9.9088  -21.6453
            24  C1b C    11.1143  -23.7299
            25  C1a C     8.7265  -22.3281
            26  C1a C     9.9138  -24.4234
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     7   8 2
            8     6   9 2
            9     9  10 1
            10   10  11 2
            11    8  11 1
            12    5  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   12  17 1
            19    5  18 1
            20    4  19 2
            21    1  20 3
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   22  24 1
            26   23  25 1
            27   24  26 1

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