KEGG   DRUG: HalothaneHelp
Entry
D00542                      Drug                                   

Name
Halothane (JP17/USP/INN);
Fluothane (TN)
Formula
C2HBrClF3
Exact mass
195.8902
Mol weight
197.3816
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG02030  Anesthetics
  DG02027  General anesthetics
   DG02028  Inhalational anaesthetics
    DG01994  Halogenated hydrocarbons
 DG02027  General anesthetics
  DG02028  Inhalational anaesthetics
   DG01994  Halogenated hydrocarbons
 DG01994  Halogenated hydrocarbons
Enzyme substrate
 DG02855  CYP2E1 substrate
 DG01633  CYP3A substrate
Remark
Same as: C07515
ATC code: N01AB01
Efficacy
Anesthetic (inhalation)
Comment
Halogenated alkane derivative
Metabolism
Enzyme: CYP2E1 [HSA:1571], CYP3A4 [HSA:1576]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AB Halogenated hydrocarbons
     N01AB01 Halothane
      D00542  Halothane (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00542  Halothane
Drug classes of therapeutic agents [br08360.html]
 Anesthetics, analgesics and anti-inflammatory drugs
  D00542
BRITE hierarchy
Other DBs
CAS: 151-67-7
PubChem: 7847608
ChEBI: 5615
ChEMBL: CHEMBL931
DrugBank: DB01159
LigandBox: D00542
NIKKAJI: J2.555K
LinkDB All DBs
KCF data Show

ATOM        7
            1   C1d C    23.0008  -15.7383
            2   C1c C    24.2141  -16.4383
            3   X   F    21.7934  -16.4383
            4   X   F    23.0008  -14.3384
            5   X   F    22.9951  -17.1442
            6   X   Cl   24.2083  -17.8382
            7   X   Br   25.4275  -15.7442
BOND        6
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 1

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