| Entry |
|
|---|
| Name |
Terazosin hydrochloride (USP);
Terazosin hydrochloride hydrate (JAN);
Hytrin (TN) |
|---|
| Product |
|
|---|
| Generic |
TERAZOSIN (Ajanta Pharma USA), TERAZOSIN (Bionpharma), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Chartwell RX), TERAZOSIN (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), TERAZOSIN (Northwind Pharmaceuticals), TERAZOSIN (Preferred Pharmaceuticals), TERAZOSIN (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN (St Mary's Medical Park Pharmacy), TERAZOSIN HYDROCHLORIDE (Preferred Pharmaceuticals) |
|---|
| Formula |
C19H25N5O4. 2H2O. HCl
|
|---|
| Exact mass |
459.1885
|
|---|
| Mol weight |
459.92
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG03231 Antihypertensive
|
|---|
| Remark |
| Therapeutic category: | 2149 |
| Product (DG00491): | D00610<JP/US> D11585<US> |
|
|---|
| Efficacy |
Antidysuria, Antihypertensive, alpha1-Adrenergic receptor antagonist |
|---|
| Comment |
Prazosin derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07215 | alpha-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CA Alpha-adrenoreceptor antagonists
G04CA03 Terazosin
D00610 Terazosin hydrochloride (USP) <JP/US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Alpha-adrenergic Blocking Agents
Terazosin
D00610 Terazosin hydrochloride (USP)
Genitourinary Agents
Benign Prostatic Hypertrophy Agents
Terazosin
D00610 Terazosin hydrochloride (USP)
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
214 Antihypertensives
2149 Others
D00610 Terazosin hydrochloride (USP); Terazosin hydrochloride hydrate (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
D00610 Terazosin hydrochloride
DG03231 Antihypertensive
DG00491 Terazosin
D00610 Terazosin hydrochloride
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D00610 Terazosin hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D00610 Terazosin hydrochloride (USP) <JP/US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
DG03231 Antihypertensive
DG00491 Terazosin
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 31
1 C8y C 31.5616 -18.9123
2 C8y C 31.5616 -17.5048
3 C8x C 32.7916 -19.6220
4 C8y C 30.3553 -19.6220
5 N5x N 30.3553 -16.8247
6 C8x C 32.7916 -16.8247
7 C8y C 33.9921 -18.9123
8 N5x N 29.1488 -18.9123
9 N1a N 30.3553 -21.0235
10 C8y C 29.1488 -17.5048
11 C8y C 33.9921 -17.5048
12 O2a O 35.2223 -19.6220
13 N1y N 27.9365 -16.8247
14 O2a O 35.2223 -16.8247
15 C1a C 36.4286 -18.9063
16 C1x C 27.9365 -15.4290
17 C1x C 26.7184 -17.5048
18 C1a C 36.4286 -17.5167
19 C1x C 26.7184 -14.7195
20 C1x C 25.5119 -16.8247
21 N1y N 25.5119 -15.4290
22 C5a C 24.2600 -14.7132
23 C1y C 23.0787 -15.4020
24 O5a O 24.3238 -13.3005
25 C1x C 23.0787 -16.8020
26 O2x O 21.7472 -14.9694
27 C1x C 20.9243 -16.1020
28 C1x C 21.7472 -17.2346
29 O0 O 41.8575 -18.0785
30 X Cl 41.1600 -15.7500
31 O0 O 41.8575 -18.0785
BOND 31
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 6 11 2
11 7 12 1
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 16 19 1
19 17 20 1
20 19 21 1
21 7 11 1
22 8 10 1
23 20 21 1
24 21 22 1
25 22 23 1
26 22 24 2
27 23 25 1
28 23 26 1
29 26 27 1
30 27 28 1
31 25 28 1
BRACKET 1 39.5500 -19.0400 39.5500 -17.3600
1 42.6300 -17.3600 42.6300 -19.0400
1 2
ORIGINAL 1 29
REPEAT 1 31
|
|---|
