| Entry |
|
|---|
| Name |
Terazosin hydrochloride anhydrous |
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| Product |
|
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| Generic |
TERAZOSIN (A-S Medication Solutions), TERAZOSIN (A-S Medication Solutions), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (Aphena Pharma Solutions - Tennessee), TERAZOSIN (AvKARE), TERAZOSIN (AvPAK), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Bryant Ranch Prepack), TERAZOSIN (Jubilant Cadista Pharmaceuticals), TERAZOSIN (NuCare Pharmaceuticals), TERAZOSIN (Proficient Rx LP), TERAZOSIN (Proficient Rx LP), TERAZOSIN (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN (REMEDYREPACK), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Aphena Pharma Solutions - Tennessee), TERAZOSIN HYDROCHLORIDE (Apnar Pharma LP), TERAZOSIN HYDROCHLORIDE (Golden State Medical Supply) |
|---|
| Formula |
C19H25N5O4. HCl
|
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| Exact mass |
423.1673
|
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| Mol weight |
423.89
|
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| Structure |
|
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| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG03231 Antihypertensive
|
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| Remark |
| Product (DG00491): | D00610<JP/US> D11585<US> |
|
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| Efficacy |
Antidysuria, Antihypertensive, alpha1-Adrenergic receptor antagonist |
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| Disease |
|
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| Comment |
Prazosin derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G04 UROLOGICALS
G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
G04CA Alpha-adrenoreceptor antagonists
G04CA03 Terazosin
D11585 Terazosin hydrochloride anhydrous <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
D11585 Terazosin hydrochloride anhydrous
DG03231 Antihypertensive
DG00491 Terazosin
D11585 Terazosin hydrochloride anhydrous
Drug classes [BR:br08332]
Cardiovascular agent
DG03231 Antihypertensive
D11585 Terazosin hydrochloride anhydrous
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D11585 Terazosin hydrochloride anhydrous <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01457 alpha1-Adrenergic receptor antagonist
DG00491 Terazosin
DG03231 Antihypertensive
DG00491 Terazosin
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8y C 18.0600 -17.9200
2 C8y C 18.0600 -16.5200
3 C8x C 19.2500 -18.6200
4 C8y C 16.8700 -18.6200
5 N5x N 16.8700 -15.8200
6 C8x C 19.2500 -15.8200
7 C8y C 20.5100 -17.9200
8 N5x N 15.6100 -17.9200
9 N1a N 16.8700 -20.0200
10 C8y C 15.6100 -16.5200
11 C8y C 20.5100 -16.5200
12 O2a O 21.7000 -18.6200
13 N1y N 14.4200 -15.8200
14 O2a O 21.7000 -15.8200
15 C1a C 22.8900 -17.9200
16 C1x C 14.4200 -14.4200
17 C1x C 13.2300 -16.5200
18 C1a C 22.8900 -16.5200
19 C1x C 13.2300 -13.7200
20 C1x C 11.9700 -15.8200
21 N1y N 11.9700 -14.4200
22 C5a C 10.7800 -13.7200
23 C1y C 9.5900 -14.4200
24 O5a O 10.7800 -12.3200
25 C1x C 9.5900 -15.8200
26 O2x O 8.2600 -14.0000
27 C1x C 7.4200 -15.1200
28 C1x C 8.2600 -16.2400
29 X Cl 23.4500 -12.2500
BOND 31
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 4 9 1
9 5 10 2
10 6 11 2
11 7 12 1
12 10 13 1
13 11 14 1
14 12 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 16 19 1
19 17 20 1
20 19 21 1
21 7 11 1
22 8 10 1
23 20 21 1
24 21 22 1
25 22 23 1
26 22 24 2
27 23 25 1
28 23 26 1
29 26 27 1
30 27 28 1
31 25 28 1
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