KEGG   DRUG: Interferon gamma-1bHelp
Entry
D00747                      Drug                                   

Name
Interferon gamma-1b (USAN/INN);
Actimmune (TN)
Product
Formula
C734H1166N204O216S5
Exact mass
16454.513
Mol weight
16464.674
Sequence
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN
FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE
LSPAAKTGKR KRSQMLFRGR
  Type
Peptide
Class
Antineoplastic
 DG01752  Interferone
Remark
ATC code: L03AB03
Chemical structure group: DG00737
Product (DG00737): D00747<US> D03357<JP>
Efficacy
Antineoplastic, Immunomodulator, Biological response modifier
Target
IFNGR1 (CD119) [HSA:3459] [KO:K05132]
IFNGR2 [HSA:3460] [KO:K05133]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  JAK-STAT signaling pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05200  Pathways in cancer
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AB Interferons
     L03AB03 Interferon gamma
      D00747  Interferon gamma-1b (USAN/INN) <US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunomodulators
   Interferon Gamma-1b, Recombinant
    D00747  Interferon gamma-1b (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   Interferon receptors
    IFNGR1 (CD119)
     D00747  Interferon gamma-1b (USAN/INN) <US>
    IFNGR2
     D00747  Interferon gamma-1b (USAN/INN) <US>
Antineoplastics [br08340.html]
 D00747
BRITE hierarchy
Other DBs
CAS: 98059-61-1
PubChem: 7847812
ChEBI: 5939
DrugBank: DB00033
LinkDB All DBs

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