Homo sapiens (human): 3459
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Entry
3459 CDS
T01001
Symbol
IFNGR1, CD119, IFNGR, IMD27A, IMD27B
Name
(RefSeq) interferon gamma receptor 1
KO
K05132
interferon gamma receptor 1
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04066
HIF-1 signaling pathway
hsa04217
Necroptosis
hsa04380
Osteoclast differentiation
hsa04630
JAK-STAT signaling pathway
hsa04650
Natural killer cell mediated cytotoxicity
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa05140
Leishmaniasis
hsa05142
Chagas disease
hsa05145
Toxoplasmosis
hsa05152
Tuberculosis
hsa05164
Influenza A
hsa05167
Kaposi sarcoma-associated herpesvirus infection
hsa05168
Herpes simplex virus 1 infection
hsa05200
Pathways in cancer
hsa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05321
Inflammatory bowel disease
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06162
Hepatitis B virus (HBV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06219
JAK-STAT signaling (cancer)
nt06229
MHC presentation (cancer)
nt06263
Hepatocellular carcinoma
nt06266
Non-small cell lung cancer
nt06276
Chronic myeloid leukemia
nt06518
JAK-STAT signaling
nt06527
Necroptosis
Element
N00053
Cytokine-Jak-STAT signaling pathway
N00185
KSHV MIR2 to cell surface molecule-endocytosis
N01559
Type II interferon to Jak-STAT signaling pathway
N01662
IFN-RIPK1/3 signaling pathway
Disease
H00089
IFN-gamma/IL-12 axis
H00342
Tuberculosis
H00412
Hepatitis B
Drug target
Interferon gamma (
DG00737
):
D00747
<US>
D03357
<JP>
D08805
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
3459 (IFNGR1)
04066 HIF-1 signaling pathway
3459 (IFNGR1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
3459 (IFNGR1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
3459 (IFNGR1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
3459 (IFNGR1)
04658 Th1 and Th2 cell differentiation
3459 (IFNGR1)
04659 Th17 cell differentiation
3459 (IFNGR1)
09158 Development and regeneration
04380 Osteoclast differentiation
3459 (IFNGR1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
3459 (IFNGR1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
3459 (IFNGR1)
09172 Infectious disease: viral
05164 Influenza A
3459 (IFNGR1)
05168 Herpes simplex virus 1 infection
3459 (IFNGR1)
05167 Kaposi sarcoma-associated herpesvirus infection
3459 (IFNGR1)
09171 Infectious disease: bacterial
05152 Tuberculosis
3459 (IFNGR1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3459 (IFNGR1)
05140 Leishmaniasis
3459 (IFNGR1)
05142 Chagas disease
3459 (IFNGR1)
09163 Immune disease
05321 Inflammatory bowel disease
3459 (IFNGR1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
hsa04050
]
3459 (IFNGR1)
04090 CD molecules [BR:
hsa04090
]
3459 (IFNGR1)
Cytokine receptors [BR:
hsa04050
]
Interleukin receptor families
IFN receptor family
3459 (IFNGR1)
CD molecules [BR:
hsa04090
]
Proteins
3459 (IFNGR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IFNGR1_D2
IFNGR1_transm
Tissue_fac
Interfer-bind
CR4_N
Motif
Other DBs
NCBI-GeneID:
3459
NCBI-ProteinID:
NP_000407
OMIM:
107470
HGNC:
5439
Ensembl:
ENSG00000027697
Pharos:
P15260
(Tbio)
UniProt:
P15260
A0A0S2Z3Y2
Structure
PDB
LinkDB
All DBs
Position
6:complement(137197484..137219385)
Genome browser
AA seq
489 aa
AA seq
DB search
MALLFLLPLVMQGVSRAEMGTADLGPSSVPTPTNVTIESYNMNPIVYWEYQIMPQVPVFT
VEVKNYGVKNSEWIDACINISHHYCNISDHVGDPSNSLWVRVKARVGQKESAYAKSEEFA
VCRDGKIGPPKLDIRKEEKQIMIDIFHPSVFVNGDEQEVDYDPETTCYIRVYNVYVRMNG
SEIQYKILTQKEDDCDEIQCQLAIPVSSLNSQYCVSAEGVLHVWGVTTEKSKEVCITIFN
SSIKGSLWIPVVAALLLFLVLSLVFICFYIKKINPLKEKSIILPKSLISVVRSATLETKP
ESKYVSLITSYQPFSLEKEVVCEEPLSPATVPGMHTEDNPGKVEHTEELSSITEVVTTEE
NIPDVVPGSHLTPIERESSSPLSSNQSEPGSIALNSYHSRNCSESDHSRNGFDTDSSCLE
SHSSLSDSEFPPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYR
PTEDSKEFS
NT seq
1470 nt
NT seq
+upstream
nt +downstream
nt
atggctctcctctttctcctaccccttgtcatgcagggtgtgagcagggctgagatgggc
accgcggatctggggccgtcctcagtgcctacaccaactaatgttacaattgaatcctat
aacatgaaccctatcgtatattgggagtaccagatcatgccacaggtccctgtttttacc
gtagaggtaaagaactatggtgttaagaattcagaatggattgatgcctgcatcaatatt
tctcatcattattgtaatatttctgatcatgttggtgatccatcaaattctctttgggtc
agagttaaagccagggttggacaaaaagaatctgcctatgcaaagtcagaagaatttgct
gtatgccgagatggaaaaattggaccacctaaactggatatcagaaaggaggagaagcaa
atcatgattgacatatttcacccttcagtttttgtaaatggagacgagcaggaagtcgat
tatgatcccgaaactacctgttacattagggtgtacaatgtgtatgtgagaatgaacgga
agtgagatccagtataaaatactcacgcagaaggaagatgattgtgacgagattcagtgc
cagttagcgattccagtatcctcactgaattctcagtactgtgtttcagcagaaggagtc
ttacatgtgtggggtgttacaactgaaaagtcaaaagaagtttgtattaccattttcaat
agcagtataaaaggttctctttggattccagttgttgctgctttactactctttctagtg
cttagcctggtattcatctgtttttatattaagaaaattaatccattgaaggaaaaaagc
ataatattacccaagtccttgatctctgtggtaagaagtgctactttagagacaaaacct
gaatcaaaatatgtatcactcatcacgtcataccagccattttccttagaaaaggaggtg
gtctgtgaagagccgttgtctccagcaacagttccaggcatgcataccgaagacaatcca
ggaaaagtggaacatacagaagaactttctagtataacagaagtggtgactactgaagaa
aatattcctgacgtggtcccgggcagccatctgactccaatagagagagagagttcttca
cctttaagtagtaaccagtctgaacctggcagcatcgctttaaactcgtatcactccaga
aattgttctgagagtgatcactccagaaatggttttgatactgattccagctgtctggaa
tcacatagctccttatctgactcagaatttcccccaaataataaaggtgaaataaaaaca
gaaggacaagagctcataaccgtaataaaagcccccacctcctttggttatgataaacca
catgtgctagtggatctacttgtggatgatagcggtaaagagtccttgattggttataga
ccaacagaagattccaaagaattttcatga
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