KEGG ORTHOLOGY: K05133

ORTHOLOGY: K05133

Entry

K05133                      KO

Symbol

IFNGR2

Name

interferon gamma receptor 2

Pathway

map04060

Cytokine-cytokine receptor interaction

map04066

HIF-1 signaling pathway

map04217

Necroptosis

map04380

Osteoclast differentiation

map04630

JAK-STAT signaling pathway

map04650

Natural killer cell mediated cytotoxicity

map04658

Th1 and Th2 cell differentiation

map04659

Th17 cell differentiation

map05140

Leishmaniasis

map05142

Chagas disease

map05145

Toxoplasmosis

map05152

Tuberculosis

map05164

Influenza A

map05168

Herpes simplex virus 1 infection

map05200

Pathways in cancer

map05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

map05321

Inflammatory bowel disease

Disease

H00089

IFN-gamma/IL-12 axis

H00342

Tuberculosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
   04066 HIF-1 signaling pathway
    K05133  IFNGR2; interferon gamma receptor 2
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05133  IFNGR2; interferon gamma receptor 2
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05133  IFNGR2; interferon gamma receptor 2
09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05133  IFNGR2; interferon gamma receptor 2
   04658 Th1 and Th2 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
   04659 Th17 cell differentiation
    K05133  IFNGR2; interferon gamma receptor 2
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05133  IFNGR2; interferon gamma receptor 2
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05133  IFNGR2; interferon gamma receptor 2
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05133  IFNGR2; interferon gamma receptor 2
  09172 Infectious disease: viral
   05164 Influenza A
    K05133  IFNGR2; interferon gamma receptor 2
   05168 Herpes simplex virus 1 infection
    K05133  IFNGR2; interferon gamma receptor 2
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05133  IFNGR2; interferon gamma receptor 2
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05133  IFNGR2; interferon gamma receptor 2
   05140 Leishmaniasis
    K05133  IFNGR2; interferon gamma receptor 2
   05142 Chagas disease
    K05133  IFNGR2; interferon gamma receptor 2
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05133  IFNGR2; interferon gamma receptor 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05133  IFNGR2; interferon gamma receptor 2
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  IFN receptor family
   K05133  IFNGR2; interferon gamma receptor 2

Other DBs

GO:

0004906

Genes

HSA:	3460(IFNGR2)

PTR:	470077(IFNGR2)

PPS:	100988947(IFNGR2)

GGO:	101144355(IFNGR2)

PON:	100442383(IFNGR2)

PPYG:

129022516(IFNGR2)

NLE:	105738709(IFNGR2)

HMH:	116482637(IFNGR2)

SSYN:

129482941(IFNGR2)

MCC:	699489(IFNGR2)

MCF:	102138221(IFNGR2)

MTHB:

126951668

MNI:	105472941(IFNGR2)

CSAB:

103216867(IFNGR2)

CATY:

105575379(IFNGR2)

PANU:

100137246(IFNGR2)

TGE:	112620311(IFNGR2)

MLEU:

105553170(IFNGR2)

RRO:	104658778(IFNGR2)

RBB:	108536857(IFNGR2)

TFN:	117095714(IFNGR2)

PTEH:

111525329(IFNGR2)

CANG:

105524763(IFNGR2)

CJC:	100389763(IFNGR2)

SBQ:	101050965(IFNGR2)

CIMI:

108302512(IFNGR2)

ANAN:

105713478(IFNGR2)

CSYR:

103269363(IFNGR2)

MMUR:

105861514(IFNGR2)

LCAT:

123630699(IFNGR2)

PCOQ:

105820775(IFNGR2)

OGA:	100957974(IFNGR2)

MMU:	15980(Ifngr2)

MCAL:

110311588(Ifngr2)

MPAH:

110330069(Ifngr2)

RNO:	360697(Ifngr2)

MCOC:

116086134(Ifngr2)

ANU:	117718220(Ifngr2)

MUN:	110541673(Ifngr2)

CGE:	100768877(Ifngr2)

MAUA:

101828108(Ifngr2)

PROB:

127227515(Ifngr2)

PLEU:

114698434(Ifngr2)

MORG:

121461788(Ifngr2)

MFOT:

126515265

AAMP:

119825404(Ifngr2)

NGI:	103736453(Ifngr2)

HGL:	101724858(Ifngr2)

CPOC:

100714935(Ifngr2)

CCAN:

109686803(Ifngr2)

DORD:

105994023(Ifngr2)

DSP:	122114285(Ifngr2)

PLOP:

125351499(Ifngr2)

NCAR:

124992912

MMMA:

107136144(Ifngr2)

OCU:

100338854

OPI:	101527415(IFNGR2)

TUP:	102481577(IFNGR2)

GVR:	103585995(IFNGR2)

CFA:	487739(IFNGR2)

CLUD:

112661608(IFNGR2)

VVP:	112909266(IFNGR2)

VLG:	121479429(IFNGR2)

NPO:	129502066(IFNGR2)

AML:	100481672(IFNGR2)

UMR:	103673221(IFNGR2)

UAH:	113264675(IFNGR2)

UAR:	123784207(IFNGR2)

ELK:

111155682

LLV:

125095012

MPUF:

101673958(IFNGR2)

MNP:	132012363(IFNGR2)

MLK:	131825325(IFNGR2)

NVS:	122908329(IFNGR2)

EJU:	114218085(IFNGR2)

ZCA:	113918583(IFNGR2)

MLX:	118018832(IFNGR2)

NSU:	110570023(IFNGR2)

LWW:	102748762(IFNGR2)

FCA:	101092286(IFNGR2)

PYU:	121035991(IFNGR2)

PCOO:

112849760(IFNGR2)

PBG:	122491220(IFNGR2)

PVIV:

125174887(IFNGR2)

LRUF:

124526582

PTG:	102955729(IFNGR2)

PPAD:

109249716(IFNGR2)

PUC:

125921709

AJU:

106966456

HHV:	120229426(IFNGR2)

BTA:	514889(IFNGR2)

BOM:	102281523(IFNGR2)

BIU:	109569763(IFNGR2)

BBUB:

102393764(IFNGR2)

BBIS:

105004619(IFNGR2)

CHX:	102191269(IFNGR2)

OAS:	101122484(IFNGR2)

BTAX:

128047334(IFNGR2)

ODA:	120854372(IFNGR2)

CCAD:

122428752(IFNGR2)

MBEZ:

129552631(IFNGR2)

SSC:	100126864(IFNGR2)

CFR:	102523264(IFNGR2)

CBAI:

105070232(IFNGR2)

CDK:	105089867(IFNGR2)

VPC:	102531183(IFNGR2)

BACU:

102997804(IFNGR2)

BMUS:

118894350(IFNGR2)

LVE:	103081741(IFNGR2)

OOR:	101279441(IFNGR2)

DLE:	111163885(IFNGR2)

PCAD:

102997040(IFNGR2)

PSIU:

116752565(IFNGR2)

NASI:

112408543(IFNGR2)

ECB:	100063333(IFNGR2)

EPZ:	103549109(IFNGR2)

EAI:	106832838(IFNGR2)

MYB:	102260069(IFNGR2)

MYD:	102751646(IFNGR2)

MMYO:

118675501(IFNGR2)

MLF:	102422535(IFNGR2)

MDT:	132229839(IFNGR2)

PKL:	118716064(IFNGR2)

EFUS:

103289926(IFNGR2)

MNA:	107537453(IFNGR2)

DRO:	112308734(IFNGR2)

SHON:

119000289(IFNGR2)

AJM:	119035735(IFNGR2)

PDIC:

118498608(IFNGR2)

PHAS:

123828042(IFNGR2)

MMF:	118617140(IFNGR2)

PPAM:

129072512(IFNGR2)

HAI:	109373230(IFNGR2)

RFQ:	117036042(IFNGR2)

PALE:

102877930(IFNGR2)

PGIG:

120598794(IFNGR2)

PVP:	105295851(IFNGR2)

RAY:	107519538(IFNGR2)

MJV:	108385993(IFNGR2)

TOD:	119257088(IFNGR2)

SARA:

101558386(IFNGR2)

SETR:

126026073(IFNGR2)

LAV:	100667304(IFNGR2)

TMU:

101361970

ETF:	101640830(IFNGR2)

DNM:	101425494(IFNGR2)

MDO:	103106298(IFNGR2)

GAS:	123242452(IFNGR2)

SHR:	100929576(IFNGR2)

AFZ:

127553870

PCW:	110214784(IFNGR2)

TVP:	118838172(IFNGR2)

OAA:	100083438(IFNGR2)

GGA:	418502(IFNGR2)

PCOC:

116242121(IFNGR2)

MGP:	100542511(IFNGR2)

CJO:	107323014(IFNGR2)

TPAI:

128076355(IFNGR2)

LMUT:

125697195(IFNGR2)

NMEL:

110402478(IFNGR2)

APLA:

101790789(IFNGR2)

ACYG:

106043434(IFNGR2)

CATA:

118247661(IFNGR2)

AFUL:

116488163(IFNGR2)

TGU:	100217912(IFNGR2)

SCAN:

103824420(IFNGR2)

PMOA:

120503406(IFNGR2)

OTC:

121334745

PRUF:

121356336(IFNGR2)

GFR:	102044820(IFNGR2)

FAB:	101814771(IFNGR2)

OMA:	130252009(IFNGR2)

PHI:

102110714

PMAJ:

107199716

CCAE:

111929263

CCW:	104698064(IFNGR2)

CBRC:

103621834(IFNGR2)

ETL:

114072364

ZLE:	135443798(IFNGR2)

ACHL:

103803230(IFNGR2)

SVG:	106861742(IFNGR2)

MMEA:

130583755

HRT:	120749097(IFNGR2)

FPG:	101919933(IFNGR2)

FCH:	102054741(IFNGR2)

CCRI:

104167679(IFNGR2)

NNT:	104403388(IFNGR2)

SHAB:

115601539(IFNGR2)

ACUN:

113477857(IFNGR2)

TALA:

104359820(IFNGR2)

ACHC:

115343830(IFNGR2)

HALD:

104315189(IFNGR2)

HLE:	104835890(IFNGR2)

AGEN:

126053194

GCL:

127029452

CSTI:

104551797(IFNGR2)

LDI:	104341618(IFNGR2)

MNB:	103773877(IFNGR2)

DPUB:

104306429(IFNGR2)

AVIT:

104271752

BRHI:

104488528(IFNGR2)

EGZ:	104128225(IFNGR2)

NNI:	104020120(IFNGR2)

PCRI:

104030404(IFNGR2)

PCAO:

104044565 104052259

PADL:

103920255(IFNGR2)

AFOR:

103901968(IFNGR2)

FGA:	104070905(IFNGR2)

GSTE:

104252480(IFNGR2)

CLV:	102097051(IFNGR2)

MUI:	104535234(IFNGR2)

PGUU:

104459971(IFNGR2)

PLET:

104627150(IFNGR2)

CMAC:

104474922(IFNGR2)

CUCA:

104064789(IFNGR2)

TEO:	104379546(IFNGR2)

BREG:

104631125(IFNGR2)

OHA:	104328368(IFNGR2)

ACAR:

104521006(IFNGR2)

CPEA:

104395004(IFNGR2)

CVF:	104295175(IFNGR2)

RTD:	128907471(IFNGR2)

AAM:	106494952(IFNGR2)

AROW:

112971821(IFNGR2)

NPD:	112953613(IFNGR2)

TGT:	104566672(IFNGR2)

DNE:	112988215(IFNGR2)

SCAM:

104139451(IFNGR2)

ASN:	102384623(IFNGR2)

AMJ:	102568595(IFNGR2)

CPOO:

109305779(IFNGR2)

GGN:	109302329(IFNGR2)

PSS:	102452317(IFNGR2)

CMY:	102929704(IFNGR2)

CCAY:

125644251(IFNGR2)

DCC:	119849712(IFNGR2)

CPIC:

101942504(IFNGR2)

TST:	117867154(IFNGR2)

CABI:

116829957(IFNGR2)

MRV:	120398127(IFNGR2)

ACS:	103278369(ifngr2)

ASAO:

132771879

PVT:	110080392(IFNGR2)

SUND:

121926273(IFNGR2)

PBI:	103049152(IFNGR2)

PMUR:

107290470(IFNGR2)

CTIG:

120296956

TSR:

106546647

PGUT:

117676037(IFNGR2)

APRI:

131199419(IFNGR2)

PTEX:

113436268(IFNGR2)

VKO:	123029099(IFNGR2)

PMUA:

114596051(IFNGR2)

PRAF:

128412985(IFNGR2)

ZVI:	118084879(IFNGR2)

HCG:	128349113(IFNGR2)

GJA:	107121928(IFNGR2)

STOW:

125430734(IFNGR2)

EMC:	129325489(IFNGR2)

XLA:	100037016 100101283 108707874 108707875

XTR:	100485298(ifngr2.2) 100485464(ifngr2.1)

RTEM:

120927904(IFNGR2)

BBUF:

120994525

BGAR:

122930810

MUO:	115458909 115469739(IFNGR2)

GSH:	117362610(IFNGR2)

SRX:

SANH:

SGH:

CCAR:

AMEX:

103047432(ifngr2)

ONL:	109194437(ifngr2-2)

OAU:

116314989

GAF:	122839747(ifngr2)

CSEM:

103391492

POV:

109637424

SSEN:

122765129

LCF:	108897140(ifngr2)

SDU:

111228112

SLAL:

111663447

XGL:	120801444(ifngr2)

MALB:

109951993

SASA:

106581880 106586855(IFNGR2)

OTW:	112225269 112243284

OMY:	100301644(ifngr2a) 110501419(ifngr2b)

SALP:

111959969 112069301

SFM:	108922312(ifngr2)

PKI:

AANG:

LOC:

ARUT:

Reference

PMID:8124716

Authors

Soh J, Donnelly RJ, Kotenko S, Mariano TM, Cook JR, Wang N, Emanuel S, Schwartz B, Miki T, Pestka S

Title

Identification and sequence of an accessory factor required for activation of the human interferon gamma receptor.

Journal

Cell 76:793-802 (1994)
DOI:10.1016/0092-8674(94)90354-9

Sequence

[hsa:3460]

Reference

PMID:11282540

Authors

Bernabei P, Allione A, Rigamonti L, Bosticardo M, Losana G, Borghi I, Forni G, Novelli F

Title

Regulation of interferon-gamma receptor (INF-gammaR) chains: a peculiar way to rule the life and death of human lymphocytes.

Journal

Eur Cytokine Netw 12:6-14 (2001)

LinkDB

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