Homo sapiens (human): 3460
Help
Entry
3460 CDS
T01001
Symbol
IFNGR2, AF-1, IFGR2, IFNGT1, IMD28
Name
(RefSeq) interferon gamma receptor 2
KO
K05133
interferon gamma receptor 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04060
Cytokine-cytokine receptor interaction
hsa04066
HIF-1 signaling pathway
hsa04217
Necroptosis
hsa04380
Osteoclast differentiation
hsa04630
JAK-STAT signaling pathway
hsa04650
Natural killer cell mediated cytotoxicity
hsa04658
Th1 and Th2 cell differentiation
hsa04659
Th17 cell differentiation
hsa05140
Leishmaniasis
hsa05142
Chagas disease
hsa05145
Toxoplasmosis
hsa05152
Tuberculosis
hsa05164
Influenza A
hsa05168
Herpes simplex virus 1 infection
hsa05200
Pathways in cancer
hsa05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hsa05321
Inflammatory bowel disease
Network
nt06160
Human T-cell leukemia virus 1 (HTLV-1)
nt06162
Hepatitis B virus (HBV)
nt06164
Kaposi sarcoma-associated herpesvirus (KSHV)
nt06165
Epstein-Barr virus (EBV)
nt06219
JAK-STAT signaling (cancer)
nt06263
Hepatocellular carcinoma
nt06266
Non-small cell lung cancer
nt06276
Chronic myeloid leukemia
nt06518
JAK-STAT signaling
nt06527
Necroptosis
Element
N00053
Cytokine-Jak-STAT signaling pathway
N01559
Type II interferon to Jak-STAT signaling pathway
N01662
IFN-RIPK1/3 signaling pathway
Disease
H00089
IFN-gamma/IL-12 axis
H00342
Tuberculosis
Drug target
Interferon gamma (
DG00737
):
D00747
<US>
D03357
<JP>
D08805
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
3460 (IFNGR2)
04066 HIF-1 signaling pathway
3460 (IFNGR2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
3460 (IFNGR2)
04658 Th1 and Th2 cell differentiation
3460 (IFNGR2)
04659 Th17 cell differentiation
3460 (IFNGR2)
09158 Development and regeneration
04380 Osteoclast differentiation
3460 (IFNGR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
3460 (IFNGR2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
3460 (IFNGR2)
09172 Infectious disease: viral
05164 Influenza A
3460 (IFNGR2)
09171 Infectious disease: bacterial
05152 Tuberculosis
3460 (IFNGR2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
3460 (IFNGR2)
05140 Leishmaniasis
3460 (IFNGR2)
05142 Chagas disease
3460 (IFNGR2)
09163 Immune disease
05321 Inflammatory bowel disease
3460 (IFNGR2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:
hsa04050
]
3460 (IFNGR2)
Cytokine receptors [BR:
hsa04050
]
Interleukin receptor families
IFN receptor family
3460 (IFNGR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tissue_fac
fn3
Interfer-bind
Motif
Other DBs
NCBI-GeneID:
3460
NCBI-ProteinID:
NP_005525
OMIM:
147569
HGNC:
5440
Ensembl:
ENSG00000159128
UniProt:
P38484
A8K881
Structure
PDB
PDBj
LinkDB
All DBs
Position
21:33402882..33437516
Genome browser
AA seq
337 aa
AA seq
DB search
MRPTLLWSLLLLLGVFAAAAAAPPDPLSQLPAPQHPKIRLYNAEQVLSWEPVALSNSTRP
VVYQVQFKYTDSKWFTADIMSIGVNCTQITATECDFTAASPSAGFPMDFNVTLRLRAELG
ALHSAWVTMPWFQHYRNVTVGPPENIEVTPGEGSLIIRFSSPFDIADTSTAFFCYYVHYW
EKGGIQQVKGPFRSNSISLDNLKPSRVYCLQVQAQLLWNKSNIFRVGHLSNISCYETMAD
ASTELQQVILISVGTFSLLSVLAGACFFLVLKYRGLIKYWFHTPPSIPLQIEEYLKDPTQ
PILEALDKDSSPKDDVWDSVSIISFPEKEQEDVLQTL
NT seq
1014 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccgacgctgctgtggtcgctgctgctgctgctcggagtcttcgccgccgccgcc
gcggccccgccagaccctctttcccagctgcccgctcctcagcacccgaagattcgcctg
tacaacgcagagcaggtcctgagttgggagccagtggccctgagcaatagcacgaggcct
gttgtctaccaagtgcagtttaaatacaccgacagtaaatggttcacggccgacatcatg
tccataggggtgaattgtacacagatcacagcaacagagtgtgacttcactgccgccagt
ccctcagcaggcttcccaatggatttcaatgtcactctacgccttcgagctgagctggga
gcactccattctgcctgggtgacaatgccttggtttcaacactatcggaatgtgactgtc
gggcctccagaaaacattgaggtgaccccaggagaaggctccctcatcatcaggttctcc
tctccctttgacatcgctgatacctccacggcctttttttgttattatgtccattactgg
gaaaaaggaggaatccaacaggtcaaaggccctttcagaagcaactccatttcattggat
aacttaaaaccctccagagtgtactgtttacaagtccaggcacaactgctttggaacaaa
agtaacatctttagagtcgggcatttaagcaacatatcttgctacgaaacaatggcagat
gcctccactgagcttcagcaagtcatcctgatctccgtgggaacattttcgttgctgtcg
gtgctggcaggagcctgtttcttcctggtcctgaaatatagaggcctgattaaatactgg
tttcacactccaccaagcatcccattacagatagaagagtatttaaaagacccaactcag
cccatcttagaggccttggacaaggacagctcaccaaaggatgacgtctgggactctgtg
tccattatctcgtttccggaaaaggagcaagaagatgttctccaaacgctttga
DBGET
integrated database retrieval system
