| Entry |
|
|---|
| Name |
Atracurium besylate (USP);
Atracurium besilate (INN);
Tracrium (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C53H72N2O12. (C6H5O3S)2
|
|---|
| Exact mass |
1242.5004
|
|---|
| Mol weight |
1243.4792
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG01742 Quaternary ammonium compound type muscle relaxant
|
|---|
| Remark |
| Product (DG00771): | D00758<US> |
|
|---|
| Efficacy |
Neuromuscular blocking agent |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07221 | Nicotinic cholinergic receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M03 MUSCLE RELAXANTS
M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS
M03AC Other quaternary ammonium compounds
M03AC04 Atracurium
D00758 Atracurium besylate (USP) <US>
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00771 Atracurium
D00758 Atracurium besylate
DG01742 Quaternary ammonium compound type muscle relaxant
DG00771 Atracurium
D00758 Atracurium besylate
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRN (neuronal type)
D00758 Atracurium besylate (USP) <US>
Drug groups [BR:br08330]
Musculo-skeletal system agent
DG02029 Muscle relaxant
DG01696 Peripherally-acting muscle relaxant
DG03117 Nondepolarizing neuromuscular blocking agent
DG00771 Atracurium
DG01742 Quaternary ammonium compound type muscle relaxant
DG00771 Atracurium
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 87
1 C8y C 14.4270 -12.9558
2 C1y C 15.6389 -13.6631
3 C8y C 14.4360 -11.5582
4 C8x C 13.2243 -13.6544
5 N2y N 16.8592 -12.9735 #+
6 C1b C 15.6389 -15.0517
7 C8x C 13.2243 -10.8508
8 C1x C 15.6566 -10.8595
9 C8y C 12.0037 -12.9558
10 C1x C 16.8682 -11.5672
11 C1b C 18.0709 -12.2568
12 C8y C 16.8505 -15.7504
13 C8y C 12.0037 -11.5582
14 O2a O 10.8008 -13.6544
15 C1b C 19.2825 -12.9558
16 C8x C 18.0532 -15.0430
17 C8x C 16.8505 -17.1477
18 O2a O 10.8008 -10.8508
19 C1a C 9.5892 -12.9558
20 C7a C 20.4944 -12.2568
21 C8y C 19.2648 -15.7417
22 C8x C 18.0622 -17.8377
23 C1a C 9.5892 -11.5495
24 O7a O 21.6970 -12.9558
25 O6a O 20.4854 -10.8508
26 C8y C 19.2738 -17.1390
27 O2a O 20.4767 -15.0340
28 C1b C 22.9087 -12.2481
29 O2a O 20.4767 -17.8290
30 C1a C 21.6794 -15.7327
31 C1b C 24.1206 -12.9468
32 C1a C 21.6794 -17.1300
33 C1b C 25.3322 -12.2391
34 C1b C 26.5438 -12.9381
35 C1b C 27.7555 -12.2304
36 O7a O 28.9671 -12.9291
37 C7a C 30.1787 -12.2217
38 C1b C 31.3904 -12.9204
39 O6a O 30.1700 -10.8241
40 C1b C 32.6020 -12.2217
41 N2y N 33.8139 -12.9204 #+
42 C1y C 35.0255 -13.6190
43 C1x C 33.8139 -11.5141
44 C1a C 32.5933 -13.6100
45 C8y C 36.2371 -12.9204
46 C1b C 35.0255 -15.0076
47 C1x C 35.0255 -10.8154
48 C8y C 36.2371 -11.5228
49 C8x C 37.4488 -13.6100
50 C8y C 33.8139 -15.7063
51 C8x C 37.4577 -10.8241
52 C8y C 38.6604 -12.9204
53 C8x C 32.5933 -15.0076
54 C8x C 33.8139 -17.1123
55 C8y C 38.6604 -11.5228
56 O2a O 39.8633 -13.6190
57 C8y C 31.3727 -15.7150
58 C8x C 32.6020 -17.8113
59 O2a O 39.8633 -10.8154
60 C1a C 41.0749 -12.9204
61 C8y C 31.3816 -17.1213
62 O2a O 30.1610 -15.0076
63 C1a C 41.0749 -11.5141
64 O2a O 30.1610 -17.8113
65 C1a C 28.9584 -15.7063
66 C1a C 28.9584 -17.1123
67 C1a C 18.0619 -13.6496
68 C8y C 12.8847 -17.5959
69 C8x C 11.6641 -18.2946
70 C8x C 14.0964 -18.2946
71 S4a S 12.8670 -16.1896
72 C8x C 11.6641 -19.7008
73 C8x C 14.0964 -19.7008
74 O1d O 11.4607 -16.1808
75 O1d O 14.2733 -16.1896
76 O1d O 12.8581 -14.7833 #-
77 C8x C 12.8847 -20.3994
78 C8y C 38.0671 -17.6740
79 C8x C 36.8465 -18.3815
80 C8x C 39.2787 -18.3815
81 S4a S 38.0494 -16.2765
82 C8x C 36.8465 -19.7878
83 C8x C 39.2787 -19.7878
84 O1d O 36.6431 -16.3378
85 O1d O 39.4557 -16.2765
86 O1d O 38.1107 -14.8704 #-
87 C8x C 38.0671 -20.4776
BOND 92
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 5 11 1
11 6 12 1
12 7 13 2
13 9 14 1
14 11 15 1
15 12 16 2
16 12 17 1
17 13 18 1
18 14 19 1
19 15 20 1
20 16 21 1
21 17 22 2
22 18 23 1
23 20 24 1
24 20 25 2
25 21 26 2
26 21 27 1
27 24 28 1
28 26 29 1
29 27 30 1
30 28 31 1
31 29 32 1
32 31 33 1
33 33 34 1
34 34 35 1
35 35 36 1
36 36 37 1
37 37 38 1
38 37 39 2
39 38 40 1
40 40 41 1
41 41 42 1
42 41 43 1
43 41 44 1
44 42 45 1
45 42 46 1
46 43 47 1
47 45 48 2
48 45 49 1
49 46 50 1
50 48 51 1
51 49 52 2
52 50 53 2
53 50 54 1
54 51 55 2
55 52 56 1
56 53 57 1
57 54 58 2
58 55 59 1
59 56 60 1
60 57 61 2
61 57 62 1
62 59 63 1
63 61 64 1
64 62 65 1
65 64 66 1
66 8 10 1
67 9 13 1
68 22 26 1
69 47 48 1
70 52 55 1
71 58 61 1
72 67 5 1
73 68 69 1
74 68 70 2
75 68 71 1
76 69 72 2
77 70 73 1
78 71 74 2
79 71 75 2
80 71 76 1
81 72 77 1
82 73 77 2
83 78 79 1
84 78 80 2
85 78 81 1
86 79 82 2
87 80 83 1
88 81 84 2
89 81 85 2
90 81 86 1
91 82 87 1
92 83 87 2
|
|---|
