Homo sapiens (human): 55584
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Entry
55584 CDS
T01001
Symbol
CHRNA9, HSA243342, NACHRA9
Name
(RefSeq) cholinergic receptor nicotinic alpha 9 subunit
KO
K04810
nicotinic acetylcholine receptor alpha-9
Organism
hsa
Homo sapiens (human)
Pathway
hsa04080
Neuroactive ligand-receptor interaction
hsa05207
Chemical carcinogenesis - receptor activation
Network
nt06210
ERK signaling (cancer)
nt06214
PI3K signaling (cancer)
Element
N01350
NNK/NNN to PI3K signaling pathway
N01353
E2 to RAS-ERK signaling pathway
Drug target
Acetylcholine (
DG01133
):
D00999
<JP/US>
Atracurium (
DG00771
):
D00758
<US>
Cisatracurium:
D00759
<US>
Cytisinicline:
D07770
Dimethyltubocurarine:
D07272
Doxacurium chloride:
D00760
Fazadinium bromide:
D07273
Hexamethonium bromide:
D02204
Lobeline (
DG01287
):
D02202
D02364
D08138
Mecamylamine (
DG00252
):
D00611
<US>
Mivacurium chloride:
D00763
Nicotine (
DG00994
):
D03365
<JP/US>
D05156
D05157
Pancuronium (
DG00769
):
D00492
Pipecuronium bromide:
D00764
Rocuronium bromide:
D00765
<JP/US>
Tubocurarine (
DG00767
):
D02207
D08655
Vecuronium (
DG00770
):
D00767
<US>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
55584 (CHRNA9)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
55584 (CHRNA9)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
55584 (CHRNA9)
Ion channels [BR:
hsa04040
]
Ligand-gated channels
Acetylcholine (nicotinic)
55584 (CHRNA9)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neur_chan_LBD
Neur_chan_memb
Motif
Other DBs
NCBI-GeneID:
55584
NCBI-ProteinID:
NP_060051
OMIM:
605116
HGNC:
14079
Ensembl:
ENSG00000174343
UniProt:
Q9UGM1
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:40335333..40355217
Genome browser
AA seq
479 aa
AA seq
DB search
MNWSHSCISFCWIYFAASRLRAAETADGKYAQKLFNDLFEDYSNALRPVEDTDKVLNVTL
QITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLY
NKADDESSEPVNTNVVLRYDGLITWDAPAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNG
NQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFY
IVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIG
KYYIATMALITASTALTIMVMNIHFCGAEARPVPHWARVVILKYMSRVLFVYDVGESCLS
PHHSRERDHLTKVYSKLPESNLKAARNKDLSRKKDMNKRLKNDLGCQGKNPQEAESYCAQ
YKVLTRNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFIMVFVMTILIIARAD
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgaactggtcccattcctgcatctccttttgctggatctactttgctgcttccagactg
agagctgcagagacggcagatggaaaatatgctcagaagttgtttaatgacctttttgaa
gattattctaatgctcttcgtccagtggaagatacagataaagtcctgaatgtgaccctg
cagattacgctctctcagattaaggatatggatgaaagaaaccaaattctgactgcttat
ttgtggatccgccaaatctggcacgatgcctatctcacgtgggaccgagatcagtacgat
ggcctagactccatcaggatccccagtgacctcgtgtggaggccagacatcgtcttatat
aacaaggctgatgatgaatcttcagagcctgtgaacaccaatgtggtcctgcggtatgat
gggctgatcacctgggatgcaccggccatcaccaaaagctcctgtgtggtggatgtcacc
tacttcccttttgacaaccagcagtgcaacctgacttttggttcctggacctacaatggc
aatcaggtggacatattcaacgccttggacagcggagatctctctgacttcattgaagat
gtggaatgggaggtccatggcatgcccgctgtgaagaatgtgatctcctatggctgctgc
tctgagccttacccggatgtcacattcaccctccttctgaagaggaggtcctcgttctat
atcgtcaacctcctcatcccatgcgtcctcatatcttttctggctcctctgagtttttat
ctcccagcagcctccggagaaaaggtctccctgggagtgaccatcctgttggccatgact
gtatttcagctaatggtggcagaaatcatgccggcctcagaaaatgtgcccctgataggt
aaatactacatagccacgatggccctgatcacagcctccactgcgttgaccatcatggtg
atgaatatccacttctgtggggccgaggcccggccggtgccacactgggccagggtggtc
atcctgaaatacatgtccagggtcttgtttgtctatgatgtgggtgaaagctgcctcagc
ccgcaccacagtagagagcgggaccacctcacgaaagtttatagcaaactcccagagtct
aacctgaaagcagccaggaacaaagacctttccagaaagaaggacatgaacaaacgctta
aagaacgacctgggctgccagggtaagaaccctcaggaggccgagagttactgtgcacag
tacaaagtgctgacgaggaatattgagtacatcgccaagtgcctcaaagaccacaaggcc
accaattccaaggggagtgaatggaagaaggtggcgaaagtcatagaccgattcttcatg
tggatttttttcattatggtgtttgtgatgactattttgatcatagcaagagcggattag
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