| Entry |
|
|---|
| Name |
Milnacipran hydrochloride (JAN/USAN);
Savella (TN);
Toledomin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C15H22N2O. HCl
|
|---|
| Exact mass |
282.1499
|
|---|
| Mol weight |
282.8089
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01658 Serotonin and norepinephrine reuptake inhibitor (SNRI)
|
|---|
| Remark |
| Therapeutic category: | 1179 |
| Product (DG00960): | D01107<JP/US> |
|
|---|
| Efficacy |
Antidepressant, Serotonin-noradrenaline reuptake inhibitor (SNRI) |
|---|
| Comment |
selective serotonin norepinephrine reuptake inhibitor (SNRI)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07234 | Neurotransmitter transporter inhibitors |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX17 Milnacipran
D01107 Milnacipran hydrochloride (JAN/USAN) <JP/US>
USP drug classification [BR:br08302]
Central Nervous System Agents
Fibromyalgia Agents
Milnacipran
D01107 Milnacipran hydrochloride (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D01107 Milnacipran hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D01107 Milnacipran hydrochloride (JAN/USAN) <JP/US>
SLC6A4 (HTT)
D01107 Milnacipran hydrochloride (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D01107
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D01107
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8x C 19.8786 -14.8387
2 C8x C 19.8786 -16.2385
3 C8x C 21.0938 -16.9384
4 C8y C 22.3018 -16.2385
5 C8x C 22.3018 -14.8387
6 C8x C 21.0938 -14.1388
7 C5a C 23.7016 -16.2385
8 C1x C 22.3159 -18.6704
9 C1y C 23.7157 -18.6704
10 C1z C 23.0089 -17.4543
11 C1b C 24.4086 -19.8793
12 O5a O 23.7645 -14.8387
13 N1c N 25.1014 -16.2385
14 C1b C 25.8013 -15.0262
15 C1b C 25.8013 -17.4506
16 C1a C 27.2011 -17.4474
17 C1a C 27.2011 -15.0225
18 N1a N 25.8084 -19.8837
19 X Cl 30.3116 -17.8220
BOND 19
1 8 10 1
2 10 9 1
3 3 4 2
4 9 11 1 #Up
5 10 4 1 #Down
6 10 7 1
7 4 5 1
8 7 12 2
9 5 6 2
10 7 13 1
11 6 1 1
12 13 14 1
13 13 15 1
14 15 16 1
15 1 2 2
16 14 17 1
17 2 3 1
18 11 18 1
19 8 9 1
|
|---|
