| Entry |
|
|---|
| Name |
Bucladesine sodium (JAN);
Actosin (TN) |
|---|
| Formula |
C18H23N5O8P. Na
|
|---|
| Exact mass |
491.1182
|
|---|
| Mol weight |
491.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01703 Cardiotonic
|
|---|
| Remark |
| Product (DG00230): | D01238<JP> |
|
|---|
| Efficacy |
Anti-ulcerative (skin), Cardiotonic, Phosphodiesterase inhibitor |
|---|
| Comment |
Cyclic AMP derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04923 | Regulation of lipolysis in adipocytes |
| hsa04925 | Aldosterone synthesis and secretion |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CE Phosphodiesterase inhibitors
C01CE04 Bucladesine
D01238 Bucladesine sodium (JAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
21 Cardiovascular agents
211 Cardiotonics
2119 Others
D01238 Bucladesine sodium (JAN)
26 Epidermides
269 Miscellaneous
2699 Others
D01238 Bucladesine sodium (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG00230 Bucladesine
D01238 Bucladesine sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Phosphodiesterases
PDE
D01238 Bucladesine sodium (JAN) <JP>
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG00230 Bucladesine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 33
1 C8y C 26.7279 -11.4252
2 N5x N 27.4398 -12.6360
3 C1b C 29.5370 -11.4028
4 C5a C 28.8250 -10.1920
5 N1b N 27.4204 -10.2031
6 C1y C 20.1522 -14.0671
7 C1y C 19.7826 -12.7028
8 C1x C 18.4164 -12.3407
9 O2x O 17.4198 -13.3428
10 P1b P 17.7892 -14.7070
11 O2x O 19.1554 -15.0691
12 C1y C 21.5622 -14.0681
13 C1y C 22.0001 -12.6599
14 O2x O 20.8588 -11.9009
15 C8y C 24.6374 -12.6614
16 N5x N 25.3494 -13.8721
17 C8x C 26.7540 -13.8610
18 C8y C 25.3300 -11.4395
19 C8x C 23.2972 -10.8361
20 N4y N 23.3088 -12.2349
21 N5x N 24.6261 -10.3965
22 O1c O 16.3793 -14.7065
23 O1c O 17.7790 -16.1134 #-
24 O7a O 22.2553 -15.2820
25 O5a O 29.5126 -8.9715
26 C7a C 21.5459 -16.4970
27 C1b C 22.2435 -17.7187
28 O6a O 20.1390 -16.4902
29 C1b C 23.6599 -17.7256
30 C1a C 24.3473 -18.9297
31 C1b C 30.9399 -11.3915
32 C1a C 31.6577 -12.6120
33 Z Na 17.6395 -17.5110 #+
BOND 35
1 6 7 1
2 15 16 1
3 16 17 2
4 17 2 1
5 1 18 1
6 18 15 2
7 7 8 1 #Up
8 8 9 1
9 9 10 1
10 19 20 1
11 20 15 1
12 18 21 1
13 21 19 2
14 13 20 1 #Up
15 10 11 1
16 10 22 2
17 6 11 1 #Down
18 10 23 1
19 12 24 1 #Down
20 4 25 2
21 1 2 2
22 12 13 1
23 13 14 1
24 24 26 1
25 14 7 1
26 26 27 1
27 6 12 1
28 3 4 1
29 4 5 1
30 26 28 2
31 5 1 1
32 27 29 1
33 29 30 1
34 3 31 1
35 31 32 1
|
|---|
