KEGG   DRUG: Bucumolol hydrochlorideHelp
Entry
D01492                      Drug                                   

Name
Bucumolol hydrochloride (JP17)
Formula
C17H23NO4. HCl
Exact mass
341.1394
Mol weight
341.8298
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
Efficacy
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB1 [HSA:153] [KO:K04141]
ADRB2 [HSA:154] [KO:K04142]
  Pathway
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB1
     D01492  Bucumolol hydrochloride (JP17)
    ADRB2
     D01492  Bucumolol hydrochloride (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01492  Bucumolol hydrochloride
BRITE hierarchy
Other DBs
CAS: 36556-75-9
PubChem: 7848555
ChEBI: 31315
LigandBox: D01492
LinkDB All DBs
KCF data Show

ATOM        23
            1   X   Cl   29.6100  -17.0800
            2   C8y C    19.6000  -15.7500
            3   O2a O    19.6000  -14.3500
            4   C1b C    20.7900  -13.7200
            5   C1c C    21.9800  -14.4200
            6   C1b C    23.2400  -13.7200
            7   N1b N    24.4300  -14.4200
            8   C1d C    25.6200  -13.7200
            9   O1a O    21.9800  -15.8200
            10  C1a C    26.8800  -14.4200
            11  C1a C    25.6200  -12.3200
            12  C1a C    26.8800  -13.0200
            13  C8y C    15.9600  -16.4500
            14  C8x C    15.9600  -17.8500
            15  C8x C    17.1500  -18.5500
            16  O7x O    17.1500  -15.7500
            17  C8y C    18.3400  -16.4500
            18  C8y C    18.3400  -17.8500
            19  C8y C    19.5300  -18.5500
            20  C8x C    20.7900  -17.9200
            21  C8x C    20.7900  -16.5200
            22  O6a O    14.7000  -15.7500
            23  C1a C    19.5300  -20.0200
BOND        23
            1     8  12 1
            2     6   7 1
            3     3   4 1
            4     7   8 1
            5    13  14 1
            6    14  15 2
            7    15  18 1
            8    17  16 1
            9    16  13 1
            10    5   9 1
            11    4   5 1
            12    8  10 1
            13    2   3 1
            14   17  18 2
            15   18  19 1
            16   19  20 2
            17   20  21 1
            18   21   2 2
            19    2  17 1
            20    8  11 1
            21   13  22 2
            22    5   6 1
            23   19  23 1

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