| Entry |
|
|---|
| Name |
Setiptiline maleate (JAN);
Tecipul (TN) |
|---|
| Formula |
C19H19N. C4H4O4
|
|---|
| Exact mass |
377.1627
|
|---|
| Mol weight |
377.433
|
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| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
Neuropsychiatric agent
DG01729 Tetracyclic antidepressant
DG03077 Noradrenergic and specific serotonergic antidepressant (NaSSA)
|
|---|
| Remark |
| Therapeutic category: | 1179 |
| Product (DG01231): | D02034<JP> |
|
|---|
| Efficacy |
Antidepressant, alpha2-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
|---|
| Structure map |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
117 Psychotropics
1179 Others
D02034 Setiptiline maleate (JAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG01231 Setiptiline
D02034 Setiptiline maleate
Neuropsychiatric agent
DG01729 Tetracyclic antidepressant
DG01231 Setiptiline
D02034 Setiptiline maleate
DG03077 Noradrenergic and specific serotonergic antidepressant (NaSSA)
DG01231 Setiptiline
D02034 Setiptiline maleate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D02034 Setiptiline maleate (JAN) <JP>
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01465 alpha-Adrenergic receptor antagonist
DG01460 alpha2-Adrenergic receptor antagonist
DG01231 Setiptiline
Neuropsychiatric agent
DG01729 Tetracyclic antidepressant
DG01231 Setiptiline
DG03077 Noradrenergic and specific serotonergic antidepressant (NaSSA)
DG01231 Setiptiline
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C2b C 36.5609 -16.2201
2 C2b C 38.2962 -16.2201
3 C6a C 35.8668 -17.4223
4 O6a O 34.4786 -17.4232
5 O6a O 36.5617 -18.6250
6 C6a C 38.9903 -17.4223
7 O6a O 40.3785 -17.4223
8 O6a O 38.2958 -18.6253
9 C2y C 27.9934 -17.6494
10 C8y C 27.1513 -16.5398
11 C8y C 27.4865 -15.1830
12 C1x C 28.7475 -14.6049
13 C2y C 29.3992 -17.6746
14 C8y C 30.0011 -15.2272
15 C8y C 30.2876 -16.5959
16 C8x C 26.4794 -14.2146
17 C8x C 25.1374 -14.6027
18 C8x C 24.8022 -15.9595
19 C8x C 25.8093 -16.9276
20 C8x C 31.6188 -17.0330
21 C8x C 32.6630 -16.0986
22 C8x C 32.3766 -14.7299
23 C8x C 31.0452 -14.2928
24 C1x C 27.2717 -18.8490
25 N1y N 27.9499 -20.0738
26 C1x C 29.3557 -20.0991
27 C1x C 30.0773 -18.8994
28 C1a C 27.2159 -21.2942
BOND 30
1 1 2 2
2 1 3 1
3 3 4 1
4 3 5 2
5 2 6 1
6 6 7 2
7 6 8 1
8 11 12 1
9 9 13 2
10 12 14 1
11 10 11 1
12 13 15 1
13 9 10 1
14 14 15 1
15 11 16 2
16 16 17 1
17 17 18 2
18 18 19 1
19 10 19 2
20 15 20 2
21 20 21 1
22 21 22 2
23 22 23 1
24 14 23 2
25 9 24 1
26 24 25 1
27 25 26 1
28 26 27 1
29 13 27 1
30 25 28 1
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