| Entry |
|
|---|
| Name |
Dibucaine hydrochloride (JP18/USP);
Nupercaine hydrochloride (TN);
Percamin (TN) |
|---|
| Formula |
C20H29N3O2. HCl
|
|---|
| Exact mass |
379.2027
|
|---|
| Mol weight |
379.92
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Product (mixture): | D04022<JP> D04699<JP> D04816<JP> D04844<JP> |
|
|---|
| Efficacy |
Anesthetic (local) |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AD Local anesthetics
C05AD04 Cinchocaine
D02220 Dibucaine hydrochloride (JP18/USP)
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AB Anesthetics for topical use
D04AB02 Cinchocaine
D02220 Dibucaine hydrochloride (JP18/USP)
N NERVOUS SYSTEM
N01 ANESTHETICS
N01B ANESTHETICS, LOCAL
N01BB Amides
N01BB06 Cinchocaine
D02220 Dibucaine hydrochloride (JP18/USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01H LOCAL ANESTHETICS
S01HA Local anesthetics
S01HA06 Cinchocaine
D02220 Dibucaine hydrochloride (JP18/USP)
S02 OTOLOGICALS
S02D OTHER OTOLOGICALS
S02DA Analgesics and anesthetics
S02DA04 Cinchocaine
D02220 Dibucaine hydrochloride (JP18/USP)
Classification of Japanese OTC drugs [BR:br08313]
Agents for urogenital organs and anus
30 Hemorrhoid drugs for external use
D02220 Dibucaine hydrochloride (JP18/USP)
Agents for integumentary system
57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
D02220 Dibucaine hydrochloride (JP18/USP)
D02220 Dibucaine hydrochloride (JP18/USP)
Agents for dental and stomatological use
75 Toothache and pyorrhea remedies
D02220 Dibucaine hydrochloride (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Dibucaine
D02220 Dibucaine hydrochloride (JP18/USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01673 Amide type local anesthetic
DG00297 Dibucaine
D02220 Dibucaine hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN2A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN3A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN4A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN5A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN8A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN9A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN10A
D02220 Dibucaine hydrochloride (JP18/USP)
SCN11A
D02220 Dibucaine hydrochloride (JP18/USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02220 Dibucaine hydrochloride
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG01675 Local anesthetic
DG01673 Amide type local anesthetic
DG00297 Dibucaine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 26
1 C8x C 22.7901 -15.3180
2 C8x C 22.7901 -16.7282
3 C8x C 24.0113 -17.4333
4 C8y C 25.2326 -16.7282
5 C8y C 25.2326 -15.3180
6 C8x C 24.0113 -14.6130
7 N5x N 26.4538 -17.4333
8 C8y C 27.6750 -16.7282
9 C8x C 27.6750 -15.3180
10 C8y C 26.4538 -14.6130
11 O2a O 28.8813 -17.4247
12 C5a C 26.4538 -13.2028
13 N1b N 27.6772 -12.4965
14 C1b C 28.8823 -13.1925
15 C1b C 30.0778 -12.5023
16 N1c N 31.2779 -13.1955
17 O5a O 25.2347 -12.4989
18 C1b C 32.4759 -12.5039
19 C1b C 31.2779 -14.6127
20 C1a C 32.4790 -15.3064
21 C1a C 33.6748 -13.1962
22 C1b C 30.0783 -16.7337
23 C1b C 31.2777 -17.4263
24 C1b C 32.4759 -16.7345
25 C1a C 33.6747 -17.4267
26 X Cl 36.8900 -15.3300
BOND 26
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 5 10 1
12 8 11 1
13 10 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 12 17 2
19 16 18 1
20 16 19 1
21 19 20 1
22 18 21 1
23 11 22 1
24 22 23 1
25 23 24 1
26 24 25 1
|
|---|
