KEGG   DRUG: Aptazapine maleateHelp
Entry
D02972                      Drug                                   

Name
Aptazapine maleate (USAN)
Formula
C16H19N3. C4H4O4
Exact mass
369.1689
Mol weight
369.4143
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01465  alpha-Adrenergic receptor antagonist
   DG01460  alpha2-Adrenergic receptor antagonist
Neuropsychiatric agent
 DG01728  Tricyclic antidepressant
Efficacy
Antidepressant, alpha2-Adrenergic receptor antagonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D02972  Aptazapine maleate (USAN)
BRITE hierarchy
Other DBs
CAS: 71576-41-5
PubChem: 17397129
ChEMBL: CHEMBL2106459
LigandBox: D02972
NIKKAJI: J400.156G
LinkDB All DBs
KCF data Show

ATOM        27
            1   C8y C    25.8255  -13.7176
            2   C1x C    24.6357  -13.0877
            3   N4y N    23.3059  -13.6476
            4   C8y C    22.9560  -14.9774
            5   C8y C    26.1054  -15.1174
            6   C1y C    23.7958  -16.1671
            7   N1y N    25.1956  -16.1671
            8   C1x C    25.8954  -17.3569
            9   C1x C    25.1956  -18.5467
            10  N1y N    23.7958  -18.5467
            11  C1x C    23.0960  -17.3569
            12  C8x C    26.8753  -12.8077
            13  C8x C    28.2051  -13.2977
            14  C8x C    28.4850  -14.6974
            15  C8x C    27.3652  -15.6073
            16  C8x C    21.5563  -14.9774
            17  C8x C    21.0663  -13.7176
            18  C8x C    22.1862  -12.8777
            19  C1a C    23.0960  -19.8065
            20  O6a O    30.9346  -15.9572
            21  C6a C    32.3343  -15.9572
            22  O6a O    32.9642  -17.1470
            23  C2b C    32.9642  -14.7674
            24  C2b C    34.6439  -14.7674
            25  C6a C    35.3438  -15.9572
            26  O6a O    36.6735  -15.9572
            27  O6a O    34.6439  -17.1470
BOND        29
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11   6 1
            13    1  12 1
            14   12  13 2
            15   13  14 1
            16   14  15 2
            17    5  15 1
            18    4  16 2
            19   16  17 1
            20   17  18 2
            21    3  18 1
            22   10  19 1
            23   20  21 1
            24   21  22 2
            25   21  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   25  27 1

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