| Entry |
|
|---|
| Name |
Armodafinil (USAN/INN);
Nuvigil (TN) |
|---|
| Product |
|
|---|
| Generic |
ARMODAFINIL (Aurobindo Pharma Limited), ARMODAFINIL (Bryant Ranch Prepack), ARMODAFINIL (Bryant Ranch Prepack), ARMODAFINIL (DirectRx), ARMODAFINIL (Direct_Rx), ARMODAFINIL (Mylan Pharmaceuticals), ARMODAFINIL (Natco Pharma USA LLC), ARMODAFINIL (Preferred Pharmaceuticals), ARMODAFINIL (Preferred Pharmaceuticals), ARMODAFINIL (Quality Care Products LLC), ARMODAFINIL (Sandoz), ARMODAFINIL (Teva Pharmaceuticals USA), ARMODAFINIL (direct rx) |
|---|
| Formula |
C15H15NO2S
|
|---|
| Exact mass |
273.0824
|
|---|
| Mol weight |
273.35
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01971 Agents for narcolepsy
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG02925 CYP3A5 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Stimulant (central) |
|---|
| Disease |
|
|---|
| Comment |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP3A5 [HSA: 1577]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06BA Centrally acting sympathomimetics
N06BA13 Armodafinil
D03215 Armodafinil (USAN/INN) <US>
USP drug classification [BR:br08302]
Sleep Disorder Agents
Wakefulness Promoting Agents
Armodafinil
D03215 Armodafinil (USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01971 Agents for narcolepsy
D03215 Armodafinil
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D03215 Armodafinil
DG02925 CYP3A5 substrate
D03215 Armodafinil
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A3 (DAT1)
D03215 Armodafinil (USAN/INN) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03215
|
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| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 19
1 C8x C 14.9817 -17.5728
2 C8x C 14.9817 -18.9709
3 C8x C 16.1954 -19.6699
4 C8x C 17.4021 -18.9709
5 C8y C 17.4021 -17.5728
6 C8x C 16.1954 -16.8736
7 C1c C 18.6134 -16.8746
8 C8y C 19.8238 -17.5747
9 C8x C 19.8172 -18.9707
10 C8x C 21.0276 -19.6708
11 C8x C 22.2391 -18.9725
12 C8x C 22.2401 -17.5745
13 C8x C 21.0296 -16.8745
14 S4a S 18.6042 -15.4754
15 C1b C 19.8113 -14.7679
16 C5a C 19.8019 -13.3689
17 O3c O 17.3684 -14.7731
18 O5a O 18.5631 -12.6648
19 N1a N 21.0008 -12.6658
BOND 20
1 4 5 1
2 5 6 2
3 8 9 2
4 9 10 1
5 10 11 2
6 11 12 1
7 12 13 2
8 13 8 1
9 6 1 1
10 7 14 1
11 5 7 1
12 7 8 1
13 1 2 2
14 2 3 1
15 14 15 1 #Down
16 15 16 1
17 3 4 2
18 14 17 2
19 16 18 2
20 16 19 1
|
|---|
