Entry |
|
Name |
Codeine polistirex (USAN) |
Class |
|
Remark |
Product (DG01076): | D02101<JP> D03580<US> |
|
Efficacy |
Antitussive, Opioid receptor agonist |
Comment |
Opium alkaloid
Active form of prodrug: Morphine [DR: D08233]
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Metabolism |
Enzyme: UGT2B7 [HSA: 7364], UGT2B4 [HSA: 7363]; CYP3A4 [HSA: 1576], CYP2D6 [HSA: 1565]
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R05 COUGH AND COLD PREPARATIONS
R05D COUGH SUPPRESSANTS, EXCL. COMBINATIONS WITH EXPECTORANTS
R05DA Opium alkaloids and derivatives
R05DA04 Codeine
D03579 Codeine polistirex (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG01076 Codeine
D03579 Codeine polistirex
Analgesic
DG01984 Opioid analgesics
DG01076 Codeine
D03579 Codeine polistirex
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01076 Codeine
D03579 Codeine polistirex
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01076 Codeine
D03579 Codeine polistirex
DG02924 UGT substrate
DG03189 UGT2B4 substrate
DG01076 Codeine
D03579 Codeine polistirex
DG03190 UGT2B7 substrate
DG01076 Codeine
D03579 Codeine polistirex
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D03579 Codeine polistirex (USAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03579
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG01563 mu-Opioid receptor agonist
DG01076 Codeine
Analgesic
DG01984 Opioid analgesics
DG01076 Codeine
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG01076 Codeine
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01076 Codeine
DG02924 UGT substrate
DG03189 UGT2B4 substrate
DG01076 Codeine
DG03190 UGT2B7 substrate
DG01076 Codeine
Prodrugs [br08324.html]
DG01076
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Other DBs |
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LinkDB |
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