KEGG   DRUG: DextroamphetamineHelp
Entry
D03740                      Drug                                   

Name
Dextroamphetamine (USAN);
Dexamfetamine (INN)
Formula
C9H13N
Exact mass
135.1048
Mol weight
135.2062
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Neuropsychiatric agent
 DG01970  Agents for ADHD
Remark
Same as: C07884
ATC code: N06BA02
Chemical structure group: DG00967
Product (DG00967): D02078<US>
Efficacy
Stimulant (central)
Comment
Compoment of Biphetamine (TN)
Target
SLC18A2 (VMAT2) [HSA:6571] [KO:K08155]
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
  Pathway
hsa04721  Synaptic vesicle cycle
hsa04728  Dopaminergic synapse
hsa05031  Amphetamine addiction
Interaction
Drug interaction
Structure map
map07234  Neurotransmitter transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA02 Dexamfetamine
      D03740  Dextroamphetamine (USAN)
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Amphetamines
   Dextroamphetamine
    D03740  Dextroamphetamine (USAN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D03740  Dextroamphetamine (USAN)
    SLC6A3 (DAT1)
     D03740  Dextroamphetamine (USAN)
   SLC18
    SLC18A2 (VMAT2)
     D03740  Dextroamphetamine (USAN)
Prodrugs [br08324.html]
 D03740
BRITE hierarchy
Other DBs
CAS: 51-64-9
PubChem: 17397829
ChEBI: 4469
ChEMBL: CHEMBL612
DrugBank: DB01576
PDB-CCD: 1WE[PDBj]
LigandBox: D03740
NIKKAJI: J4.121A
LinkDB All DBs
KCF data Show

ATOM        10
            1   C8y C    18.0880  -15.4844
            2   C8x C    16.8267  -14.7837
            3   C8x C    18.0880  -16.8859
            4   C1b C    19.2792  -14.7837
            5   C8x C    15.6355  -15.4844
            6   C8x C    16.8267  -17.5866
            7   C1c C    20.4704  -15.4844
            8   C8x C    15.6355  -16.8859
            9   N1a N    21.6616  -14.7837
            10  C1a C    20.4704  -16.8859
BOND        10
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     7   9 1
            9     7  10 1 #Up
            10    6   8 1

» Japanese version   » Back

DBGET integrated database retrieval system