Entry |
|
Name |
Fospropofol disodium (USAN); Aquavan (TN); Lusedra (TN) |
Formula |
C13H19O5P. 2Na
|
Exact mass |
332.0766
|
Mol weight |
332.2403
|
Structure |

|
Class |
|
Remark |
Product (DG00797): | D00549<JP/US> |
|
Efficacy |
Sedative |
Comment |
Active form of prodrug: Propofol [DR: D00549]
|
Target |
|
Pathway |
hsa04080 | Neuroactive ligand-receptor interaction |
|
Interaction |
|
Structure map |
map07230 | GABA-A receptor agonists/antagonists |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AX Other general anesthetics
N01AX10 Propofol
D04257 Fospropofol disodium (USAN)
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D04257 Fospropofol disodium (USAN)
New drug approvals in the USA [br08319.html]
New molecular entities and new therapeutic biological products
D04257
New drug approvals in the USA, Europe and Japan [br08328.html]
Approval dates by FDA, EMA and PMDA
D04257
Prodrugs [br08324.html]
D04257
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 21
1 C8y C 21.0426 -15.5979
2 C8y C 22.2600 -14.8989
3 C1c C 19.8312 -14.8989
4 C8x C 21.0426 -16.9958
5 C8y C 23.4714 -15.5979
6 O2a O 22.2657 -13.5010
7 C1a C 19.8312 -13.5010
8 C1a C 18.6196 -15.5979
9 C8x C 22.2600 -17.7005
10 C1c C 24.6888 -14.8989
11 C8x C 23.4714 -16.9958
12 C1a C 25.9004 -15.5979
13 C1a C 24.6888 -13.5010
14 C1b C 23.4729 -12.8107
15 O2b O 23.4707 -11.4102
16 P1b P 24.6665 -10.7171
17 O1c O 25.8790 -10.0171 #-
18 O1c O 23.9561 -9.4884
19 O1c O 25.3575 -11.9122 #-
20 Z Na 28.5600 -9.9400 #+
21 Z Na 28.7000 -12.0400 #+
BOND 19
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 1
11 10 12 1
12 10 13 1
13 9 11 2
14 6 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 16 18 2
19 16 19 1
|