| Entry |
|
|---|
| Name |
Tertatolol (INN) |
|---|
| Formula |
C16H25NO2S
|
|---|
| Exact mass |
295.1606
|
|---|
| Mol weight |
295.44
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiarrhythmic, Antihypertensive, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA16 Tertatolol
D07182 Tertatolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00309 Tertatolol
D07182 Tertatolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00309 Tertatolol
D07182 Tertatolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D07182 Tertatolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00309 Tertatolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00309 Tertatolol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8x C 18.1300 -17.0800
2 C8x C 18.1300 -18.4800
3 C8x C 16.8700 -19.1800
4 C8y C 15.6800 -18.4800
5 C8y C 15.6800 -17.0800
6 C8y C 16.8700 -16.3800
7 C1x C 14.4900 -19.2500
8 C1x C 13.2300 -18.5500
9 C1x C 13.2300 -17.1500
10 S2x S 14.4200 -16.3800
11 O2a O 16.8700 -15.0500
12 C1b C 18.0600 -14.3500
13 C1c C 19.2500 -15.0500
14 C1b C 20.5100 -14.3500
15 N1b N 21.7000 -15.0500
16 O1a O 19.2500 -16.3800
17 C1d C 22.9181 -14.3599
18 C1a C 24.0995 -15.0550
19 C1a C 22.8598 -12.9506
20 C1a C 24.1305 -13.6599
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 6 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 13 16 1
18 15 17 1
19 17 18 1
20 17 19 1
21 17 20 1
|
|---|
