KEGG   DRUG: Amfetamine
Entry
D07445                      Drug                                   
Name
Amfetamine (INN);
Amphetamine;
Adzenys (TN);
Dyanavel (TN)
Product
  Generic
Formula
C9H13N
Exact mass
135.1048
Mol weight
135.21
Structure
Simcomp
Remark
Same as: C07514
ATC code: N06BA01
Chemical structure group: DG00966
Product (DG00966): D07445<US> D02074<US>
Efficacy
Stimulant (central)
  Disease
Attention deficit hyperactivity disorder [DS:H01895]
Target
SLC18A2 (VMAT2) [HSA:6571] [KO:K08155]
SLC6A2 (NAT1) [HSA:6530] [KO:K05035]
SLC6A3 (DAT1) [HSA:6531] [KO:K05036]
  Pathway
hsa04721  Synaptic vesicle cycle
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse
hsa05031  Amphetamine addiction
Interaction
Structure map
map07234  Neurotransmitter transporter inhibitors
Other map
map05031  Amphetamine addiction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06B PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
    N06BA Centrally acting sympathomimetics
     N06BA01 Amfetamine
      D07445  Amfetamine (INN) <US>
USP drug classification [BR:br08302]
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Amphetamines
   Amphetamine
    D07445  Amfetamine (INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC6
    SLC6A2 (NAT1)
     D07445  Amfetamine (INN) <US>
    SLC6A3 (DAT1)
     D07445  Amfetamine (INN) <US>
   SLC18
    SLC18A2 (VMAT2)
     D07445  Amfetamine (INN) <US>
Prodrugs [br08324.html]
 D07445
Narcotics and psychotropics in Japan [br08308.html]
 Stimulants by Control Act Article 2 Appended Table and Cabinet Order
  D07445
Other DBs
CAS: 300-62-9
PubChem: 51091776
LigandBox: D07445
NIKKAJI: J231.296D
LinkDB
KCF data

ATOM        10
            1   C8y C    18.0426  -15.4812
            2   C8x C    16.8566  -14.7835
            3   C8x C    18.0426  -16.8766
            4   C1b C    19.2287  -14.7835
            5   C8x C    15.6008  -15.4812
            6   C8x C    16.8566  -17.5742
            7   C1c C    20.4845  -15.4812
            8   C8x C    15.6008  -16.8766
            9   N1a N    21.6705  -14.7835
            10  C1a C    20.4845  -16.8766
BOND        10
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 2
            6     4   7 1
            7     5   8 2
            8     7   9 1
            9     7  10 1
            10    6   8 1

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