KEGG   DRUG: BrimonidineHelp
Entry
D07540                      Drug                                   

Name
Brimonidine (INN)
Formula
C11H10BrN5
Exact mass
291.012
Mol weight
292.1346
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Remark
Same as: C07886
ATC code: D11AX21 S01EA05
Chemical structure group: DG00442
Product (DG00442): D02076<JP/US>
Efficacy
Antiglaucoma, alpha2-Adrenergic receptor agonist
Target
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Structure map
map07054  Antiglaucoma agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D11 OTHER DERMATOLOGICAL PREPARATIONS
   D11A OTHER DERMATOLOGICAL PREPARATIONS
    D11AX Other dermatologicals
     D11AX21 Brimonidine
      D07540  Brimonidine (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EA Sympathomimetics in glaucoma therapy
     S01EA05 Brimonidine
      D07540  Brimonidine (INN)
USP drug classification [BR:br08302]
 Dermatological Agents
  Brimonidine
   D07540  Brimonidine (INN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Brimonidine
    D07540  Brimonidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA2
     D07540  Brimonidine (INN)
BRITE hierarchy
Other DBs
CAS: 59803-98-4
PubChem: 51091862
ChEBI: 3175
ChEMBL: CHEMBL844
LigandBox: D07540
NIKKAJI: J23.694B
LinkDB All DBs
KCF data Show

ATOM        17
            1   C8x C    16.3100  -16.7300
            2   C8x C    16.3100  -18.1300
            3   N5x N    17.5000  -18.8300
            4   C8y C    18.7600  -18.1300
            5   C8y C    18.7600  -16.7300
            6   N5x N    17.5000  -16.0300
            7   C8x C    19.9500  -18.8300
            8   C8x C    21.1400  -18.1300
            9   C8y C    21.1400  -16.7300
            10  C8y C    19.9500  -16.0300
            11  N2x N    23.5900  -18.1300
            12  C2y C    23.5900  -16.7300
            13  N1b N    22.4000  -16.0300
            14  C1x C    24.9200  -18.5500
            15  C1x C    25.7600  -17.4300
            16  N1x N    24.9200  -16.3100
            17  X   Br   19.9500  -14.6300
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   11  12 2
            13   12  13 1
            14    9  13 1
            15   11  14 1
            16   14  15 1
            17   15  16 1
            18   12  16 1
            19   10  17 1

» Japanese version   » Back

DBGET integrated database retrieval system