| Entry |
|
|---|
| Name |
Allopurinol sodium;
Aloprim (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C5H3N4O. Na
|
|---|
| Exact mass |
158.0205
|
|---|
| Mol weight |
158.09
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
|
|---|
| Remark |
| Product (DG00779): | D00224<JP/US> D07564<US> |
|
|---|
| Efficacy |
Gout suppressant, Uric acid biosynthesis inhibitor, Xanthine oxidase inhibitor |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
CYP inhibition: CYP1A2 [HSA: 1544]
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M04 ANTIGOUT PREPARATIONS
M04A ANTIGOUT PREPARATIONS
M04AA Preparations inhibiting uric acid production
M04AA01 Allopurinol
D07564 Allopurinol sodium <US>
USP drug classification [BR:br08302]
Antigout Agents
Allopurinol
D07564 Allopurinol sodium
Antineoplastics
Antineoplastic Adjuncts/Mitigators
Allopurinol
D07564 Allopurinol sodium
Drug groups [BR:br08330]
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
DG00779 Allopurinol
D07564 Allopurinol sodium
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
DG00779 Allopurinol
D07564 Allopurinol sodium
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00779 Allopurinol
D07564 Allopurinol sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Xanthine dehydrogenase/oxidase
XDH
D07564 Allopurinol sodium <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D07564
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D07564
Drug groups [BR:br08330]
Cardiovascular agent
DG01503 Xanthine dehydrogenase inhibitor
DG00779 Allopurinol
Musculo-skeletal system agent
DG03130 Xanthin oxidase inhibitor
DG00779 Allopurinol
Metabolizing enzyme inhibitor
DG01634 CYP1A2 inhibitor
DG00779 Allopurinol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 11
1 C8y C 24.0800 -17.9200
2 C8y C 24.0800 -19.3200
3 C8y C 25.2700 -17.2200
4 N4x N 22.7500 -17.5000
5 N5x N 25.2700 -20.0200
6 C8x C 22.7500 -19.7400
7 N5x N 26.4600 -17.9200
8 O1a O 25.2700 -15.8200 #-
9 N5x N 21.9100 -18.6200
10 C8x C 26.4600 -19.3200
11 Z Na 29.6800 -18.1300 #+
BOND 11
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 3 8 1
8 4 9 1
9 5 10 2
10 6 9 2
11 7 10 1
|
|---|
