| Entry |
|
|---|
| Name |
Carteolol (INN) |
|---|
| Formula |
C16H24N2O3
|
|---|
| Exact mass |
292.1787
|
|---|
| Mol weight |
292.37
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG03231 Antihypertensive
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
|---|
| Remark |
| Product (DG00308): | D00599<JP/US> |
| Product (mixture): | D10804<JP> |
|
|---|
| Efficacy |
Antiglaucoma, beta-Adrenergic receptor antagonist |
|---|
| Comment |
Propranolol derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
|---|
| Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07A BETA BLOCKING AGENTS
C07AA Beta blocking agents, non-selective
C07AA15 Carteolol
D07624 Carteolol (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01ED Beta blocking agents
S01ED05 Carteolol
D07624 Carteolol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00308 Carteolol
D07624 Carteolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00308 Carteolol
D07624 Carteolol
DG03231 Antihypertensive
DG00308 Carteolol
D07624 Carteolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00308 Carteolol
D07624 Carteolol
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00308 Carteolol
D07624 Carteolol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB
D07624 Carteolol (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D07624
Drug groups [BR:br08330]
Cardiovascular agent
DG01466 Adrenergic receptor antagonist
DG01464 beta-Adrenergic receptor antagonist (Beta blocker)
DG00308 Carteolol
DG01653 Antiarrhythmics
DG01806 Class II antiarrhythmic agent
DG00308 Carteolol
DG03231 Antihypertensive
DG00308 Carteolol
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG00308 Carteolol
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
DG00308 Carteolol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C1x C 19.3200 -18.8300
2 C5x C 19.3200 -20.2300
3 N1x N 20.5800 -21.0000
4 C8y C 21.7700 -20.2300
5 C8y C 21.7700 -18.8300
6 C1x C 20.5800 -18.1300
7 C8x C 23.0300 -21.0000
8 C8x C 24.2200 -20.2300
9 C8x C 24.2200 -18.8300
10 C8y C 23.0300 -18.1300
11 O5x O 18.1300 -21.0000
12 O2a O 23.0300 -16.7300
13 C1b C 24.2200 -16.0300
14 C1c C 25.4100 -16.7300
15 C1b C 26.6000 -16.0300
16 O1a O 25.4100 -18.1300
17 N1b N 27.7900 -16.7300
18 C1d C 28.9800 -16.0300
19 C1a C 30.1700 -15.3300
20 C1a C 29.6800 -17.2900
21 C1a C 28.2800 -14.8400
BOND 22
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 2
8 7 8 1
9 8 9 2
10 9 10 1
11 5 10 2
12 2 11 2
13 10 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 14 16 1
18 15 17 1
19 17 18 1
20 18 19 1
21 18 20 1
22 18 21 1
|
|---|
