| Entry |
|
|---|
| Name |
Chlormadinone (INN) |
|---|
| Formula |
C21H27ClO3
|
|---|
| Exact mass |
362.1649
|
|---|
| Mol weight |
362.89
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Antineoplastic
DG01591 Androgen receptor antagonist
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00469): | D01299<JP> |
|
|---|
| Efficacy |
Menstruation disorder agent, Prostatic hyperplasia treatment, Progesterone receptor agonist, Androgen receptor antagonist |
|---|
| Comment |
Progestin, Pregnadien derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03D PROGESTOGENS
G03DB Pregnadien derivatives
G03DB06 Chlormadinone
D07670 Chlormadinone (INN)
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG00469 Chlormadinone
D07670 Chlormadinone
Hormonal agent
DG02004 Progesterone
DG00469 Chlormadinone
D07670 Chlormadinone
DG01666 Progesterone receptor agonist
DG00469 Chlormadinone
D07670 Chlormadinone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D07670 Chlormadinone (INN)
NR3C4 (AR)
D07670 Chlormadinone (INN)
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG00469 Chlormadinone
Hormonal agent
DG02004 Progesterone
DG00469 Chlormadinone
DG01666 Progesterone receptor agonist
DG00469 Chlormadinone
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C1z C 22.2255 -14.2313
2 C1z C 21.0340 -14.8622
3 C1x C 23.3470 -14.8622
4 O1a O 23.3470 -13.5304
5 C5a C 22.2255 -12.8295
6 C1y C 21.0340 -16.2640
7 C1x C 19.8424 -14.1612
8 C1a C 21.0340 -13.5304
9 C1x C 23.3470 -16.2640
10 C1a C 21.0339 -12.1285
11 O5a O 23.4170 -12.1285
12 C1y C 19.8424 -16.9650
13 C1x C 18.6508 -14.8622
14 C1y C 18.6508 -16.2640
15 C2x C 19.8424 -18.2968
16 C1z C 17.4592 -16.8949
17 C2y C 18.6508 -18.9977
18 C2y C 17.4592 -18.2968
19 C1x C 16.2676 -16.1939
20 C1a C 17.4592 -15.5631
21 X Cl 18.6507 -20.3295
22 C2x C 16.2676 -18.9977
23 C1x C 15.0760 -16.8949
24 C5x C 15.0760 -18.2968
25 O5x O 13.8844 -18.9977
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 2 8 1 #Up
8 3 9 1
9 5 10 1
10 5 11 2
11 6 12 1
12 7 13 1
13 12 14 1
14 12 15 1
15 14 16 1
16 15 17 2
17 16 18 1
18 16 19 1
19 16 20 1 #Up
20 17 21 1
21 18 22 2
22 19 23 1
23 22 24 1
24 24 25 2
25 6 9 1
26 13 14 1
27 17 18 1
28 23 24 1
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