| Entry |
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| Name |
Chlormadinone acetate (JP18/USAN);
Lutoral (TN) |
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| Formula |
C23H29ClO4
|
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| Exact mass |
404.1754
|
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| Mol weight |
404.92
|
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| Structure |
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| Simcomp |
|
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| Class |
Antineoplastic
DG01591 Androgen receptor antagonist
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
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| Remark |
| Therapeutic category: | 2478 |
| Product (DG00469): | D01299<JP> |
|
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| Efficacy |
Menstruation disorder agent, Prostatic hyperplasia treatment, Progesterone receptor agonist, Androgen receptor antagonist |
|---|
| Comment |
Progestin, Pregnadien derivative
|
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| Target |
|
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| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
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| Interaction |
|
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03D PROGESTOGENS
G03DB Pregnadien derivatives
G03DB06 Chlormadinone
D01299 Chlormadinone acetate (JP18/USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
247 Estrogen and progesterone preparations
2478 Synthetic progestins
D01299 Chlormadinone acetate (JP18/USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG00469 Chlormadinone
D01299 Chlormadinone acetate
Hormonal agent
DG02004 Progesterone
DG00469 Chlormadinone
D01299 Chlormadinone acetate
DG01666 Progesterone receptor agonist
DG00469 Chlormadinone
D01299 Chlormadinone acetate
Drug classes [BR:br08332]
Antineoplastic
DG01591 Androgen receptor antagonist
D01299 Chlormadinone acetate
Endocrine and hormonal agent
DG02004 Progesterone
D01299 Chlormadinone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D01299 Chlormadinone acetate (JP18/USAN) <JP>
NR3C4 (AR)
D01299 Chlormadinone acetate (JP18/USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D01299 Chlormadinone acetate
Drug groups [BR:br08330]
Antineoplastic
DG01591 Androgen receptor antagonist
DG00469 Chlormadinone
Hormonal agent
DG02004 Progesterone
DG00469 Chlormadinone
DG01666 Progesterone receptor agonist
DG00469 Chlormadinone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C1z C 34.0635 -15.4455
2 C1z C 32.8751 -16.1154
3 C1x C 35.2406 -16.1271
4 O7a O 35.2406 -14.7520
5 C5a C 34.1921 -14.0704
6 C1y C 32.9334 -17.4848
7 C1x C 31.7039 -15.4279
8 C1x C 35.2290 -17.4964
9 C7a C 36.4293 -15.4338
10 C1a C 32.9918 -13.3769
11 O5a O 35.3749 -13.3712
12 C1y C 31.6806 -18.1664
13 C1x C 30.5094 -16.0980
14 C1a C 37.6120 -14.7463
15 O6a O 36.4235 -16.8089
16 C1y C 30.4978 -17.4672
17 C2x C 31.6806 -19.5357
18 C1z C 29.3091 -18.1490
19 C2y C 30.4861 -20.2174
20 C2y C 29.3034 -19.5241
21 C1x C 28.1265 -17.4615
22 C1a C 29.2977 -16.7797
23 X Cl 30.5445 -21.5867
24 C2x C 28.1265 -20.2174
25 C1x C 26.9320 -18.1490
26 C5x C 26.9320 -19.5241
27 O5x O 25.7433 -20.2057
28 C1a C 32.8751 -14.7154
BOND 31
1 1 2 1
2 1 3 1
3 1 4 1 #Down
4 1 5 1 #Up
5 2 6 1
6 2 7 1
7 3 8 1
8 4 9 1
9 5 10 1
10 5 11 2
11 6 12 1
12 7 13 1
13 9 14 1
14 9 15 2
15 12 16 1
16 12 17 1
17 16 18 1
18 17 19 2
19 18 20 1
20 18 21 1
21 18 22 1 #Up
22 19 23 1
23 20 24 2
24 21 25 1
25 24 26 1
26 26 27 2
27 6 8 1
28 13 16 1
29 19 20 1
30 25 26 1
31 2 28 1 #Up
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