| Entry |
|
|---|
| Name |
Bupropion hydrobromide (USAN);
Aplenzin (TN) |
|---|
| Product |
|
|---|
| Formula |
C13H18ClNO. HBr
|
|---|
| Exact mass |
319.0339
|
|---|
| Mol weight |
320.65
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
|
|---|
| Remark |
| Product (DG00957): | D00817<US> D07938<US> |
| Product (mixture): | D10751<US> |
|
|---|
| Efficacy |
Antidepressant, Noradrenalin and dopamine reuptake inhibitor |
|---|
| Disease |
Major depressive disorder [DS: H01646] |
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AX Other antidepressants
N06AX12 Bupropion
D07938 Bupropion hydrobromide (USAN) <US>
USP drug classification [BR:br08302]
Antidepressants
Antidepressants, Other
Bupropion
D07938 Bupropion hydrobromide (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG00957 Bupropion
D07938 Bupropion hydrobromide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D07938 Bupropion hydrobromide (USAN) <US>
SLC6A3 (DAT1)
D07938 Bupropion hydrobromide (USAN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG00957 Bupropion
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 17
1 C8y C 16.3800 -16.1700
2 C8x C 16.3800 -17.5700
3 C8x C 15.1200 -18.2700
4 C8x C 13.9300 -17.5700
5 C8y C 13.9300 -16.1700
6 C8x C 15.1200 -15.4700
7 X Cl 12.6700 -15.4700
8 C5a C 17.5700 -15.4700
9 C1c C 18.7600 -16.1700
10 O5a O 17.5700 -14.0700
11 N1b N 19.9500 -15.4700
12 C1a C 18.7600 -17.5700
13 C1d C 21.1400 -16.1700
14 C1a C 22.3300 -15.4700
15 C1a C 21.1400 -17.5700
16 C1a C 22.4000 -16.8000
17 X Br 25.9700 -16.8700
BOND 16
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 1 8 1
9 8 9 1
10 8 10 2
11 9 11 1
12 9 12 1
13 11 13 1
14 13 14 1
15 13 15 1
16 13 16 1
|
|---|
