| Entry |
|
|---|
| Name |
Formoterol (INN);
Oxis (TN) |
|---|
| Formula |
C19H24N2O4
|
|---|
| Exact mass |
344.1736
|
|---|
| Mol weight |
344.40
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
Metabolizing enzyme substrate
DG02924 UGT substrate
|
|---|
| Remark |
| Product (DG01052): | D01373<US> D05277<JP/US> |
| Product (mixture): | D11036<JP/US> |
|
|---|
| Efficacy |
Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AC Selective beta-2-adrenoreceptor agonists
R03AC13 Formoterol
D07990 Formoterol (INN)
R03C ADRENERGICS FOR SYSTEMIC USE
R03CC Selective beta-2-adrenoreceptor agonists
R03CC15 Formoterol
D07990 Formoterol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01052 Formoterol
D07990 Formoterol
Metabolizing enzyme substrate
DG02924 UGT substrate
DG01052 Formoterol
D07990 Formoterol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D07990 Formoterol (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D07990
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01052 Formoterol
Metabolizing enzyme substrate
DG02924 UGT substrate
DG01052 Formoterol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 25
1 C8y C 24.5700 -21.2100
2 C8x C 23.3800 -21.9100
3 C8x C 24.5700 -19.8100
4 C1c C 25.7600 -21.9100
5 C8y C 22.1200 -21.2100
6 C8x C 23.3800 -19.1100
7 C1b C 27.0200 -21.2100
8 O1a O 25.7600 -23.3100
9 C8y C 22.1200 -19.8100
10 N1b N 20.9300 -21.9100
11 N1b N 28.2100 -21.9100
12 O1a O 20.9300 -19.1100
13 C4a C 19.7400 -21.2100
14 C1c C 29.4000 -21.2100
15 O4a O 18.4800 -21.9100
16 C1b C 30.5900 -21.9100
17 C1a C 29.4000 -19.8100
18 C8y C 31.8500 -21.2100
19 C8x C 31.8500 -19.8100
20 C8x C 33.0400 -21.9100
21 C8x C 33.0400 -19.1100
22 C8x C 34.2300 -21.2100
23 C8y C 34.2300 -19.8100
24 O2a O 35.4900 -19.0400
25 C1a C 36.6800 -19.7400
BOND 26
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 2
6 4 7 1
7 4 8 1
8 5 9 2
9 5 10 1
10 7 11 1
11 9 12 1
12 10 13 1
13 11 14 1
14 13 15 2
15 14 16 1
16 14 17 1
17 16 18 1
18 18 19 2
19 18 20 1
20 19 21 1
21 20 22 2
22 21 23 2
23 23 24 1
24 24 25 1
25 6 9 1
26 22 23 1
|
|---|
