| Entry |
|
|---|
| Name |
Gallopamil (INN) |
|---|
| Formula |
C28H40N2O5
|
|---|
| Exact mass |
484.2937
|
|---|
| Mol weight |
484.63
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Vasodilator, Calcium channel blocker |
|---|
| Comment |
Phenylalkylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C08 CALCIUM CHANNEL BLOCKERS
C08D SELECTIVE CALCIUM CHANNEL BLOCKERS WITH DIRECT CARDIAC EFFECTS
C08DA Phenylalkylamine derivatives
C08DA02 Gallopamil
D08009 Gallopamil (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG00330 Gallopamil
D08009 Gallopamil
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
DG00330 Gallopamil
D08009 Gallopamil
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Calcium channels
CACNA1-L
D08009 Gallopamil (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01575 Calcium channel blocker
DG01496 Calcium channel L type blocker
DG00330 Gallopamil
DG01653 Antiarrhythmics
DG01807 Phenylalkylamine derivative
DG00330 Gallopamil
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 35
1 C1d C 20.5800 -16.5200
2 C8y C 19.3200 -17.2200
3 C1b C 21.7700 -17.2200
4 C1c C 20.5800 -15.1200
5 C8x C 18.1300 -16.5200
6 C8x C 19.3200 -18.6200
7 C1b C 22.9600 -16.5200
8 C1a C 21.8400 -14.4200
9 C1a C 19.3900 -14.4200
10 C8y C 16.9400 -17.2200
11 C8y C 18.1300 -19.3200
12 C1b C 24.1500 -17.2200
13 C8y C 16.9400 -18.6200
14 O2a O 15.6800 -16.5200
15 N1c N 25.4100 -16.5200
16 O2a O 15.6800 -19.3200
17 C1a C 14.4900 -17.2200
18 C1b C 26.6000 -17.2200
19 C1a C 25.4100 -15.1200
20 C1a C 14.4900 -18.6200
21 C1b C 27.8600 -16.5200
22 C8y C 29.0500 -17.1500
23 C8x C 30.2400 -16.4500
24 C8x C 29.0500 -18.5500
25 C8y C 31.4300 -17.1500
26 C8x C 30.2400 -19.2500
27 C8y C 31.4300 -18.5500
28 O2a O 32.6900 -16.4500
29 C1a C 33.8800 -17.1500
30 O2a O 18.1300 -20.7200
31 C1a C 16.9400 -21.4200
32 O2a O 32.6900 -19.2500
33 C1a C 33.8800 -18.5500
34 C3b C 20.5800 -17.9200
35 N3a N 20.5800 -19.3200
BOND 36
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 4 9 1
9 5 10 1
10 6 11 2
11 7 12 1
12 10 13 2
13 10 14 1
14 12 15 1
15 13 16 1
16 14 17 1
17 15 18 1
18 15 19 1
19 16 20 1
20 18 21 1
21 21 22 1
22 22 23 1
23 22 24 2
24 23 25 2
25 24 26 1
26 25 27 1
27 25 28 1
28 28 29 1
29 11 13 1
30 26 27 2
31 11 30 1
32 30 31 1
33 27 32 1
34 32 33 1
35 1 34 1
36 34 35 3
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