KEGG   DRUG: MetaraminolHelp
Entry
D08192                      Drug                                   

Name
Metaraminol (INN)
Formula
C9H13NO2
Exact mass
167.0946
Mol weight
167.205
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01702  Phenethylamine cardiotonic
 DG01456  Adrenergic receptor agonist
  DG01450  alpha-Adrenergic receptor agonist
   DG01448  alpha1-Adrenergic receptor agonist
   DG01449  alpha2-Adrenergic receptor agonist
Remark
Same as: C07146
ATC code: C01CA09
Chemical structure group: DG00218
Efficacy
Antihypotensive, alpha-Adrenergic receptor agonist
Comment
Phenethylamine derivative
Target
ADRA1 [HSA:148 147 146] [KO:K04135 K04136 K04137]
ADRA2 [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CA Adrenergic and dopaminergic agents
     C01CA09 Metaraminol
      D08192  Metaraminol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRA1
     D08192  Metaraminol (INN)
    ADRA2
     D08192  Metaraminol (INN)
BRITE hierarchy
Other DBs
CAS: 54-49-9
PubChem: 96024882
ChEBI: 6794
ChEMBL: CHEMBL1201319
DrugBank: DB00610
LigandBox: D08192
NIKKAJI: J4.155F
LinkDB All DBs
KCF data Show

ATOM        12
            1   C8y C     8.1200  -18.6900
            2   C8x C     8.1200  -20.0900
            3   C8x C     9.3324  -20.7900
            4   C8x C    10.5449  -20.0900
            5   C8y C    10.5449  -18.6900
            6   C8x C     9.3324  -17.9900
            7   O1a O     6.9076  -17.9900
            8   C1c C    11.7760  -17.9790
            9   C1c C    12.9812  -18.6747
            10  O1a O    11.7757  -16.5901
            11  N1a N    14.1635  -17.9919
            12  C1a C    12.9816  -20.0896
BOND        12
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     8   9 1
            10    8  10 1 #Up
            11    9  11 1 #Up
            12    9  12 1

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