KEGG   DRUG: Norethisterone enantateHelp
Entry
D08285                      Drug                                   

Name
Norethisterone enantate;
Noristerat (TN)
Formula
C27H38O3
Exact mass
410.2821
Mol weight
410.5888
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Other
 DG01666  Progesterone receptor agonist
 DG02004  Progesterone
Remark
Same as: C14486
ATC code: G03AC01 G03DC02
Chemical structure group: DG00456
Product (DG00456): D00182<JP/US> D00953<US>
Efficacy
Contraceptive, Progesterone receptor agonist
Comment
Progestin
Target
NR3C3 (PGR) [HSA:5241] [KO:K08556]
  Pathway
hsa04114  Oocyte meiosis
hsa04914  Progesterone-mediated oocyte maturation
hsa04915  Estrogen signaling pathway
Interaction
Drug interaction
Structure map
map07226  Progesterone, androgen and estrogen receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
    G03AC Progestogens
     G03AC01 Norethisterone
      D08285  Norethisterone enantate
   G03D PROGESTOGENS
    G03DC Estren derivatives
     G03DC02 Norethisterone
      D08285  Norethisterone enantate
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    NR3C3 (PGR)
     D08285  Norethisterone enantate
BRITE hierarchy
Other DBs
CAS: 3836-23-5
PubChem: 96024972
ChEBI: 34894
ChEMBL: CHEMBL3187229
LigandBox: D08285
NIKKAJI: J59.376A
LinkDB All DBs
KCF data Show

ATOM        30
            1   C1z C    23.5200  -17.9200
            2   C1z C    24.6400  -17.2900
            3   C1y C    23.4500  -19.3200
            4   C1x C    22.3300  -17.2900
            5   C1a C    23.4500  -16.5900
            6   C1x C    25.8300  -17.9900
            7   O7a O    24.6400  -15.8900
            8   C3b C    25.8300  -16.5900
            9   C1y C    22.2600  -20.0200
            10  C1x C    25.8300  -19.3200
            11  C1x C    21.1400  -17.9200
            12  C7a C    24.6400  -14.5600
            13  C3a C    27.0200  -15.8900
            14  C1y C    21.1400  -19.3200
            15  C1x C    22.2600  -21.3500
            16  C1b C    25.8300  -13.8600
            17  O6a O    23.4500  -13.8600
            18  C1y C    19.9500  -20.0200
            19  C1x C    21.0700  -22.0500
            20  C2y C    19.9500  -21.3500
            21  C1x C    18.7600  -19.3200
            22  C2x C    18.7600  -22.0500
            23  C1x C    17.5700  -20.0200
            24  C5x C    17.5700  -21.3500
            25  O5x O    16.3800  -22.0500
            26  C1b C    27.0900  -14.5600
            27  C1b C    28.2800  -13.8600
            28  C1b C    29.4700  -14.5600
            29  C1b C    30.7300  -13.8600
            30  C1a C    31.9200  -14.5600
BOND        33
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Up
            5     2   6 1
            6     2   7 1 #Up
            7     2   8 1 #Down
            8     3   9 1
            9     3  10 1
            10    4  11 1
            11    7  12 1
            12    8  13 3
            13    9  14 1
            14    9  15 1
            15   12  16 1
            16   12  17 2
            17   14  18 1
            18   15  19 1
            19   18  20 1
            20   18  21 1
            21   20  22 2
            22   21  23 1
            23   22  24 1
            24   24  25 2
            25    6  10 1
            26   11  14 1
            27   19  20 1
            28   23  24 1
            29   16  26 1
            30   26  27 1
            31   27  28 1
            32   28  29 1
            33   29  30 1

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