| Entry |
|
|---|
| Name |
Norethindrone acetate (USP);
Norethisterone acetate (JAN);
Aygestin (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C22H28O3
|
|---|
| Exact mass |
340.2038
|
|---|
| Mol weight |
340.45
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG02004 Progesterone
DG01666 Progesterone receptor agonist
|
|---|
| Remark |
| Product (DG00456): | D00182<JP/US> D00953<US> |
| Product (mixture): | D04483<JP/US> D09188<JP/US> D12137<US> D12226<US> |
|
|---|
| Efficacy |
Contraceptive, Progesterone receptor agonist |
|---|
| Comment |
Progestin
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03A HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
G03AC Progestogens
G03AC01 Norethisterone
D00953 Norethindrone acetate (USP) <US>
G03D PROGESTOGENS
G03DC Estren derivatives
G03DC02 Norethisterone
D00953 Norethindrone acetate (USP) <US>
USP drug classification [BR:br08302]
Contraceptives
Oral Progestins
Norethindrone
D00953 Norethindrone acetate (USP)
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Progestins
Norethindrone
D00953 Norethindrone acetate (USP)
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00456 Norethisterone
D00953 Norethindrone acetate
DG01666 Progesterone receptor agonist
DG00456 Norethisterone
D00953 Norethindrone acetate
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG02004 Progesterone
D00953 Norethindrone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C3 (PGR)
D00953 Norethindrone acetate (USP) <US>
Drug groups [BR:br08330]
Hormonal agent
DG02004 Progesterone
DG00456 Norethisterone
DG01666 Progesterone receptor agonist
DG00456 Norethisterone
|
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| Other DBs |
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| LinkDB |
|
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| KCF data |
ATOM 25
1 C1z C 26.8820 -17.0674
2 C1z C 28.0682 -16.3895
3 C1y C 26.8705 -18.4405
4 C1x C 25.7075 -16.3836
5 C1a C 26.8762 -15.7000
6 C1x C 29.2545 -17.0791
7 O7a O 28.0567 -15.0162
8 C3b C 29.2487 -15.7000
9 C1y C 25.6842 -19.1184
10 C1x C 29.2429 -18.3822
11 C1x C 24.5155 -17.0557
12 C7a C 28.0567 -13.6548
13 C3a C 30.4292 -15.0105
14 C1y C 24.5038 -18.4231
15 C1x C 25.6842 -20.4917
16 C1a C 29.2429 -12.9710
17 O6a O 26.8762 -12.9769
18 C1y C 23.3175 -19.1009
19 C1x C 24.4921 -21.1696
20 C2y C 23.3118 -20.4800
21 C1x C 22.1371 -18.4172
22 C2x C 22.1371 -21.1636
23 C1x C 20.9508 -19.1009
24 C5x C 20.9508 -20.4800
25 O5x O 19.7588 -21.1579
BOND 28
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1 #Up
5 2 6 1
6 2 7 1 #Up
7 2 8 1 #Down
8 3 9 1
9 3 10 1
10 4 11 1
11 7 12 1
12 8 13 3
13 9 14 1
14 9 15 1
15 12 16 1
16 12 17 2
17 14 18 1
18 15 19 1
19 18 20 1
20 18 21 1
21 20 22 2
22 21 23 1
23 22 24 1
24 24 25 2
25 6 10 1
26 11 14 1
27 19 20 1
28 23 24 1
|
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