KEGG   DRUG: OxprenololHelp
Entry
D08318                      Drug                                   

Name
Oxprenolol (INN);
Oxprenolol (TN)
Formula
C15H23NO3
Exact mass
265.1678
Mol weight
265.348
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01806  Class II antiarrhythmic agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: C07AA02
Chemical structure group: DG00304
Efficacy
Antiarrhythmic, Vasodilator, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB [HSA:153 154 155] [KO:K04141 K04142 K04143]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA02 Oxprenolol
      D08318  Oxprenolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB
     D08318  Oxprenolol (INN)
BRITE hierarchy
Other DBs
CAS: 6452-71-7
PubChem: 96025005
ChEMBL: CHEMBL546
DrugBank: DB01580
LigandBox: D08318
NIKKAJI: J8.410G
LinkDB All DBs
KCF data Show

ATOM        19
            1   O2a O    20.3700  -15.6800
            2   C1b C    21.5600  -14.9800
            3   C1c C    22.8200  -15.6800
            4   C1b C    24.0100  -14.9800
            5   N1b N    25.2000  -15.6800
            6   C1c C    26.4600  -14.9800
            7   C1a C    27.6500  -15.6800
            8   O1a O    22.8200  -17.0800
            9   C1a C    26.4600  -13.5800
            10  C8y C    20.3700  -17.0800
            11  C8y C    19.1100  -17.7800
            12  C8x C    19.1100  -19.1800
            13  C8x C    20.3700  -19.8800
            14  C8x C    21.5600  -19.1800
            15  C8x C    21.5600  -17.7800
            16  O2a O    17.9200  -17.0800
            17  C1b C    16.7300  -17.7800
            18  C2b C    15.5400  -17.0800
            19  C2a C    14.3500  -17.7800
BOND        19
            1     3   4 1
            2     4   5 1
            3     5   6 1
            4     6   7 1
            5     3   8 1
            6     6   9 1
            7     1   2 1
            8     2   3 1
            9     1  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13   13  14 1
            14   14  15 2
            15   10  15 1
            16   11  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 2

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