Entry |
|
Name |
Pirmenol (INN) |
Formula |
C22H30N2O
|
Exact mass |
338.2358
|
Mol weight |
338.49
|
Structure |

|
Simcomp |
|
Class |
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01649 Class Ia antiarrhythmic agent
|
Remark |
Product (DG01381): | D01785<JP> |
|
Efficacy |
Antiarrhythmic |
Comment |
Class I antiarrhythmic agent (Ia)
|
Target |
|
Pathway |
hsa04261 | Adrenergic signaling in cardiomyocytes |
|
Interaction |
|
Structure map |
|
Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01649 Class Ia antiarrhythmic agent
DG01381 Pirmenol
D08394 Pirmenol
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Sodium channels
SCN1A
D08394 Pirmenol (INN)
SCN2A
D08394 Pirmenol (INN)
SCN3A
D08394 Pirmenol (INN)
SCN4A
D08394 Pirmenol (INN)
SCN5A
D08394 Pirmenol (INN)
SCN8A
D08394 Pirmenol (INN)
SCN9A
D08394 Pirmenol (INN)
SCN10A
D08394 Pirmenol (INN)
SCN11A
D08394 Pirmenol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01653 Antiarrhythmics
DG01652 Class I antiarrhythmic agent
DG01649 Class Ia antiarrhythmic agent
DG01381 Pirmenol
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 25
1 C8x C 19.9500 -20.3700
2 C8x C 19.9500 -21.7700
3 C8x C 21.1400 -22.4700
4 C8x C 22.3300 -21.7700
5 C8y C 22.3300 -20.3700
6 C8x C 21.1400 -19.6700
7 C1d C 23.5900 -19.6700
8 C8y C 24.7800 -20.3700
9 C8x C 24.7800 -21.7700
10 C8x C 25.9700 -22.4700
11 C8x C 27.2300 -21.7700
12 C8x C 27.2300 -20.3700
13 N5x N 25.9700 -19.6700
14 C1b C 23.5900 -18.2700
15 C1b C 24.7800 -17.5700
16 C1b C 24.7800 -16.1700
17 N1y N 25.9700 -15.4700
18 C1y C 27.2300 -16.1700
19 C1x C 28.4200 -15.4700
20 C1x C 28.4200 -14.0700
21 C1x C 27.2300 -13.3700
22 C1y C 25.9700 -14.0700
23 C1a C 24.7800 -13.3700
24 C1a C 27.2300 -17.5700
25 O1a O 22.4000 -18.9700
BOND 27
1 11 12 1
2 12 13 2
3 13 8 1
4 6 1 1
5 7 14 1
6 14 15 1
7 5 7 1
8 15 16 1
9 16 17 1
10 7 8 1
11 1 2 2
12 2 3 1
13 3 4 2
14 4 5 1
15 5 6 2
16 17 18 1
17 18 19 1
18 19 20 1
19 20 21 1
20 21 22 1
21 22 17 1
22 8 9 2
23 22 23 1 #Down
24 9 10 1
25 18 24 1 #Down
26 10 11 2
27 7 25 1
|