KEGG   DRUG: TiclopidineHelp
Entry
D08594                      Drug                                   

Name
Ticlopidine (INN);
Ticlopidin-Puren (TN)
Formula
C14H14ClNS
Exact mass
263.0535
Mol weight
263.7857
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
 DG01809  P2Y12 receptor antagonist
  DG01808  Thienopyridine
Enzyme inhibitor
 DG01634  CYP1A2 inhibitor
 DG02892  CYP2B6 inhibitor
 DG01933  CYP2C19 inhibitor
 DG01645  CYP2D6 inhibitor
Remark
Same as: C07140
ATC code: B01AC05
Chemical structure group: DG00156
Product (DG00156): D01028<JP/US>
Efficacy
Anticoagulant, Platelet aggregation inhibitor, Purinergic receptor P2Y12 antagonist
Comment
Thienopyridine derivative
Target
P2RY12 [HSA:64805] [KO:K04298]
  Pathway
hsa04611  Platelet activation
Interaction
CYP inhibition: CYP2C19 [HSA:1557], CYP1A2 [HSA:1544], CYP2B6 [HSA:1555], CYP2D6 [HSA:1565]
Drug interaction
Structure map
map07049  Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC05 Ticlopidine
      D08594  Ticlopidine (INN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Platelet Modifying Agents
   Ticlopidine
    D08594  Ticlopidine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Purine / pyrimidine
    P2RY12
     D08594  Ticlopidine (INN)
BRITE hierarchy
Other DBs
CAS: 55142-85-3
PubChem: 96025278
ChEBI: 9588
ChEMBL: CHEMBL833
DrugBank: DB00208
PDB-CCD: TIC[PDBj]
LigandBox: D08594
NIKKAJI: J11.390E
LinkDB All DBs
KCF data Show

ATOM        17
            1   C8x C    19.4600  -17.2200
            2   C8x C    19.4600  -18.6200
            3   C8x C    20.6500  -19.3200
            4   C8y C    21.9100  -18.6200
            5   C8y C    21.9100  -17.2200
            6   C8x C    20.6500  -16.5200
            7   C1b C    23.1000  -19.3200
            8   N1y N    24.2900  -18.6200
            9   C1x C    24.2900  -17.2200
            10  X   Cl   23.1000  -16.5200
            11  C1x C    25.5500  -19.3200
            12  C8y C    26.7400  -18.6200
            13  C8y C    26.7400  -17.2200
            14  C1x C    25.5500  -16.5200
            15  C8x C    28.0700  -19.0400
            16  C8x C    28.9100  -17.9200
            17  S2x S    28.0700  -16.8000
BOND        19
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    5  10 1
            11    8  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15    9  14 1
            16   12  15 1
            17   15  16 2
            18   16  17 1
            19   13  17 1

» Japanese version   » Back

DBGET integrated database retrieval system