| Entry |
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| Name |
Cediranib maleate (JAN/USAN) |
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| Formula |
C25H27FN4O3. C4H4O4
|
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| Exact mass |
566.2177
|
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| Mol weight |
566.58
|
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| Structure |
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| Simcomp |
|
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| Class |
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
|
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| Remark |
|
|---|
| Efficacy |
Antineoplastic, Angiogenesis inhibitor, Receptor tyrosine kinase inhibitor |
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| Target |
|
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L01 ANTINEOPLASTIC AGENTS
L01E PROTEIN KINASE INHIBITORS
L01EK Vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitors
L01EK02 Cediranib
D08883 Cediranib maleate (JAN/USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
DG01360 Cediranib
D08883 Cediranib maleate
Target-based classification of drugs [BR:br08310]
Protein kinases
Receptor tyrosine kinases (RTK)
VEGFR family
VEGFR1 (FLT1)
D08883 Cediranib maleate (JAN/USAN)
VEGFR2 (KDR)
D08883 Cediranib maleate (JAN/USAN)
VEGFR3 (FLT4)
D08883 Cediranib maleate (JAN/USAN)
Drug groups [BR:br08330]
Antineoplastic
DG01918 Tyrosine kinase inhibitor
DG01917 Receptor tyrosine kinase inhibitor
DG03203 VEGFR inhibitor
DG01360 Cediranib
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 C8y C 19.8247 -16.2595
2 C8y C 19.8247 -14.8641
3 C8x C 21.0108 -16.9572
4 C8y C 18.5688 -16.9572
5 N5x N 18.5688 -14.1664
6 C8x C 21.0108 -14.1664
7 C8y C 22.1969 -16.2595
8 N5x N 17.3827 -16.2595
9 C8x C 17.3827 -14.8641
10 C8y C 22.1969 -14.8641
11 O2a O 23.4528 -16.9572
12 O2a O 23.4528 -14.1664
13 C1a C 24.6389 -16.2595
14 C1b C 24.6389 -14.8641
15 O2a O 18.5690 -18.3526
16 C8y C 17.3129 -19.0504
17 C8y C 16.1268 -18.2829
18 C8y C 14.8709 -18.9806
19 C8y C 14.8707 -20.3760
20 C8x C 16.0570 -21.1435
21 C8x C 17.3129 -20.4458
22 C8x C 13.5453 -18.5620
23 C8y C 12.7080 -19.6783
24 N4x N 13.5453 -20.7946
25 C1a C 11.3126 -19.6783
26 X F 16.1268 -16.8874
27 C1b C 25.8250 -14.1664
28 C1b C 27.0112 -14.8641
29 N1y N 28.2670 -14.1664
30 C1x C 29.4532 -14.7245
31 C1x C 30.4300 -13.7477
32 C1x C 29.7323 -12.5616
33 C1x C 28.4066 -12.8407
34 C2b C 34.6860 -17.5852
35 C2b C 36.4303 -17.5852
36 C6a C 33.9883 -18.7936
37 C6a C 37.1280 -18.7936
38 O6a O 38.5233 -18.7936
39 O6a O 32.5931 -18.7936
40 O6a O 34.6765 -19.9852
41 O6a O 36.4399 -19.9852
BOND 44
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 5 9 2
9 6 10 2
10 7 11 1
11 10 12 1
12 11 13 1
13 12 14 1
14 7 10 1
15 8 9 1
16 4 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 20 21 2
23 16 21 1
24 18 22 1
25 22 23 2
26 23 24 1
27 19 24 1
28 23 25 1
29 17 26 1
30 14 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 30 31 1
35 31 32 1
36 32 33 1
37 29 33 1
38 34 35 2
39 34 36 1
40 35 37 1
41 37 38 2
42 36 39 1
43 36 40 2
44 37 41 1
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