| Entry |
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| Name |
Levamlodipine malate (USAN) |
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| Formula |
C20H25ClN2O5. C4H6O5
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| Exact mass |
542.1667
|
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| Mol weight |
542.96
|
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG03231 Antihypertensive
DG01928 Dihydropyridine calcium channel blocker
|
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| Remark |
| Product (DG03091): | D11723<US> |
|
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| Efficacy |
Antihypertensive, Vasodilator |
|---|
| Comment |
Dihydropyridine derivative
See Amlodipine [DR: D07450]
Treatment of Hypertension, Chronic stable angina, Vasospastic angina
|
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| Target |
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| Pathway |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C08 CALCIUM CHANNEL BLOCKERS
C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
C08CA Dihydropyridine derivatives
C08CA17 Levamlodipine
D08941 Levamlodipine malate (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01928 Dihydropyridine calcium channel blocker
D08941 Levamlodipine malate
Target-based classification of drugs [BR:br08310]
Ion channels
Voltage-gated ion channels
Calcium channels
CACNA1-L
D08941 Levamlodipine malate (USAN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 37
1 C2y C 14.3290 -12.1664
2 C2y C 14.3290 -13.5649
3 C1y C 15.5401 -14.2641
4 C2y C 16.7513 -13.5649
5 C2y C 16.7513 -12.1664
6 N1x N 15.5401 -11.4671
7 C1b C 17.9874 -11.4671
8 O2a O 19.1986 -12.1664
9 C1b C 20.4097 -11.4671
10 C1b C 21.6208 -12.1664
11 N1a N 22.8320 -11.4671
12 C7a C 17.9874 -14.2641
13 O7a O 19.1986 -13.5649
14 C1b C 20.4097 -14.2641
15 C1a C 21.6208 -13.5649
16 C1a C 13.1179 -11.4671
17 C7a C 13.1179 -14.2641
18 O7a O 11.9237 -13.5744
19 C8y C 15.5401 -15.6624
20 C8x C 14.3122 -16.3715
21 C8x C 14.3124 -17.7700
22 C8x C 15.5236 -18.4691
23 C8x C 16.7515 -17.7600
24 C8y C 16.7513 -16.3615
25 O6a O 13.1178 -15.6624
26 C1a C 10.7376 -14.2592
27 O6a O 17.9936 -15.4000
28 X Cl 18.0113 -16.3615
29 O6a O 27.6146 -13.8446
30 C6a C 28.8257 -14.5438
31 C1c C 30.0367 -13.8446
32 C1b C 31.2478 -14.5438
33 C6a C 32.4589 -13.8446
34 O6a O 33.6701 -14.5438
35 O6a O 28.8257 -15.9421
36 O6a O 32.4589 -12.4462
37 O1a O 30.0367 -12.4463
BOND 37
1 1 2 2
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 10 11 1
12 4 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 1 16 1
17 2 17 1
18 17 18 1
19 3 19 1 #Up
20 19 20 2
21 20 21 1
22 21 22 2
23 22 23 1
24 23 24 2
25 19 24 1
26 17 25 2
27 18 26 1
28 12 27 2
29 24 28 1
30 29 30 1
31 30 31 1
32 31 32 1
33 32 33 1
34 33 34 1
35 30 35 2
36 33 36 2
37 31 37 1 #Up
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