KEGG   DRUG: Levamlodipine maleate
Entry
D11723                      Drug                                   
Name
Levamlodipine maleate (USAN);
Conjupri (TN)
Product
  Generic
Formula
C20H25ClN2O5. C4H4O4
Exact mass
524.1562
Mol weight
524.9481
Structure
Remark
ATC code: C08CA17
Chemical structure group: DG03091
Product (DG03091): D11723<US>
Efficacy
Antihypertensive
  Disease
Hypertension [DS:H01633]
Comment
Dihydropyridine derivative
Target
CACNA1-L [HSA:775 776 778 779] [KO:K04850 K04851 K04853 K04857]
  Pathway
hsa04020  Calcium signaling pathway
hsa04260  Cardiac muscle contraction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C08 CALCIUM CHANNEL BLOCKERS
   C08C SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS
    C08CA Dihydropyridine derivatives
     C08CA17 Levamlodipine
      D11723  Levamlodipine maleate (USAN) <US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Calcium Channel Blocking Agents, Dihydropyridines
   Levamlodipine
    D11723  Levamlodipine maleate (USAN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Calcium channels
    CACNA1-L
     D11723  Levamlodipine maleate (USAN) <US>
Other DBs
CAS: 135969-53-8
PubChem: 405226589
LinkDB
KCF data

ATOM        36
            1   C2y C     8.8564  -12.9957
            2   C2y C     8.8564  -14.4005
            3   C1y C    10.1207  -15.1029
            4   C2y C    11.3148  -14.4005
            5   C2y C    11.3148  -12.9957
            6   N1x N    10.1207  -12.2933
            7   C1b C    12.5791  -12.2933
            8   O2a O    13.8434  -12.9957
            9   C1b C    15.0375  -12.2933
            10  C1b C    16.2315  -12.9957
            11  N1a N    17.4958  -12.2933
            12  C7a C    12.5791  -15.1029
            13  O7a O    13.8434  -14.4005
            14  C1b C    15.0375  -15.1029
            15  C1a C    16.2315  -14.4005
            16  C1a C     7.6623  -12.2933
            17  C7a C     7.6623  -15.1029
            18  O7a O     6.4683  -14.4708
            19  C8y C    10.1207  -16.5779
            20  C8x C     8.8564  -17.2803
            21  C8x C     8.8564  -18.6851
            22  C8x C    10.1207  -19.3875
            23  C8x C    11.3148  -18.6851
            24  C8y C    11.3148  -17.2803
            25  O6a O     7.6623  -16.5779
            26  C1a C     5.2742  -15.1029
            27  O6a O    12.5791  -16.2970
            28  X   Cl   12.5791  -17.2803
            29  C2b C    19.8800  -16.4500
            30  C2b C    21.2800  -16.4500
            31  C6a C    19.1800  -17.6624
            32  C6a C    21.9800  -17.6624
            33  O6a O    17.7802  -17.6624
            34  O6a O    19.8704  -18.8579
            35  O6a O    23.3798  -17.6624
            36  O6a O    21.2896  -18.8579
BOND        36
            1     1   2 2
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12    4  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16    1  16 1
            17    2  17 1
            18   17  18 1
            19    3  19 1 #Up
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   19  24 1
            26   17  25 2
            27   18  26 1
            28   12  27 2
            29   24  28 1
            30   29  30 2
            31   29  31 1
            32   30  32 1
            33   31  33 1
            34   31  34 2
            35   32  35 2
            36   32  36 1

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