KEGG   DRUG: Tesamorelin acetateHelp
Entry
D09015                      Drug                                   

Name
Tesamorelin acetate (USAN);
Egrifta (TN)
Product
Formula
C221H366N72O67S. (C2H4O2)x
Sequence
C6H9O-Tyr Ala Asp Ala Ile Phe Thr Asn Ser Tyr Arg Lys Leu Gly Gln
Leu Ser Ala Arg Lys Leu Leu Gln Asp Ile Met Ser Arg Gln Gln Gly
Glu Ser Asn Gln Glu Arg Gly Ala Arg Ala Arg Leu-NH2
  Type
Peptide
Remark
ATC code: H01AC06
Chemical structure group: DG00495
Product (DG00495): D09015<US>
Efficacy
Growth hormone releasing hormone receptor agonist
Comment
growth hormone-releasing hormone (GH-RH) [HSA:2691] [KO:K05260] analog
For reduction of visceral adipose tissue in patients receiving antiretroviral therapy
Target
GHRHR [HSA:2692] [KO:K04584]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
   H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
    H01AC Somatropin and somatropin agonists
     H01AC06 Tesamorelin
      D09015  Tesamorelin acetate (USAN) <US>
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Pituitary)
  Tesamorelin
   D09015  Tesamorelin acetate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Growth hormone-releasing hormone
    GHRHR
     D09015  Tesamorelin acetate (USAN) <US>
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D09015
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09015
BRITE hierarchy
Other DBs
CAS: 901758-09-6
PubChem: 96025698
LinkDB All DBs

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