KEGG   DRUG: Telmisartan and hydrochlorothiazide
Entry
D09219            Mixture   Drug                                   
Name
Telmisartan and hydrochlorothiazide (JP18);
Micombi (TN);
Micardis hct (TN)
Product
MICARDIS HCT (Boehringer Ingelheim Pharmaceuticals)
  Generic
TELMISARTAN AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Alembic Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Aurobindo Pharma Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Glenmark Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Lupin Pharmaceuticals), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Solco Healthcare LLC), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Zydus Lifesciences Limited), TELMISARTAN AND HYDROCHLOROTHIAZIDE (Zydus Pharmaceuticals USA)
Component
Telmisartan [DR:D00627], Hydrochlorothiazide [DR:D00340]
Class
Cardiovascular agent
 DG01925  Renin-angiotensin system inhibitor
 DG03231  Antihypertensive
Metabolizing enzyme substrate
 DG02924  UGT substrate
Remark
Therapeutic category: 2149
ATC code: C09DA07
Product: D09219<JP/US>
Efficacy
Antihypertensive
  Disease
Hypertension [DS:H01633]
Comment
Telmisartan is primarily metabolized by UDP-glucuronosyltransferase (UGT).
Metabolism
Enzyme: UGT [KO:K00699]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM
   C09D ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS
    C09DA Angiotensin II receptor blockers (ARBs) and diuretics
     C09DA07 Telmisartan and diuretics
      D09219  Telmisartan and hydrochlorothiazide (JP18) <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Cardiovascular Agents, Combinations
   Hydrochlorothiazide/ Telmisartan
    D09219  Telmisartan and hydrochlorothiazide (JP18)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   214  Antihypertensives
    2149  Others
     D09219  Telmisartan and hydrochlorothiazide (JP18)
Drug groups [BR:br08330]
 Cardiovascular agent
  DG01925  Renin-angiotensin system inhibitor
   D09219  Telmisartan and hydrochlorothiazide
  DG03231  Antihypertensive
   D09219  Telmisartan and hydrochlorothiazide
 Metabolizing enzyme substrate
  DG02924  UGT substrate
   D09219  Telmisartan and hydrochlorothiazide
Drug classes [BR:br08332]
 Cardiovascular agent
  DG03231  Antihypertensive
   D09219  Telmisartan and hydrochlorothiazide
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D09219  Telmisartan and hydrochlorothiazide tablets
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D09219
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D09219
Other DBs
PubChem: 96025899
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system