KEGG   DRUG: Cantuzumab ravtansineHelp
Entry
D10454                      Drug                                   

Name
Cantuzumab ravtansine (USAN)
Formula
C6570H10130N1726O2018S44(C42H59ClN3O11S2)n
Sequence
(Heavy chain)
XVQLVQSGAE VKKPGETVKI SCKASDYTFT YYGMNWVKQA PGQGLKWMGW IDTTTGEPTY
AQKFQGRIAF SLETSASTAY LQIKSLKSED TATYFCARRG PYNWYFDVWG QGTTVTVSSA
STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG
LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS
TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL
TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVM HEALHNHYTQ KSLSLSPGK
(Light chain)
DIVMTQSPLS VPVTPGEPVS ISCRSSKSLL HSNGNTYLYW FLQRPGQSPQ LLIYRMSNLV
SGVPDRFSGS GSGTAFTLRI SRVEAEDVGV YYCLQHLEYP FTFGPGTKLE LKRTVAAPSV
FIFPPSDEQL KSGTASVVCL LNNFYPREAK VQWKVDNALQ SGNSQESVTE QDSKDSTYSL
SSTLTLSKAD YEKHKVYACE VTHQGLSSPV TKSFNRGEC
(dimer; disulfide bridges: H22-H96, H146-H202, H222-L219 H228-H'228, H231-H'231, H263-H323, H369-H427, H'22-H'96, H'146-H'202, H'222-L'219, H'263-H'323, H'369-H'427, L23-L93, L139-L'199, L'23-L'93, L'139-L'199)
  Type
Peptide
Efficacy
Antineoplastic
Comment
Antibody-drug conjugate
Target
CA242
Other DBs
CAS: 868747-45-9
PubChem: 172232547
LinkDB All DBs

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