| Entry |
|
|---|
| Name |
Sotagliflozin (USAN/INN) |
|---|
| Formula |
C21H25ClO5S
|
|---|
| Exact mass |
424.1111
|
|---|
| Mol weight |
424.9382
|
|---|
| Structure |
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|---|
| Simcomp |
|
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| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Antidiabetic, SGLT inhibitor |
|---|
| Comment |
Phlorizin derivative
Treatment of type 2 diabetes
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04973 | Carbohydrate digestion and absorption |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors
A10BK06 Sotagliflozin
D10669 Sotagliflozin (USAN/INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01794 SGLT2 inhibitor
D10669 Sotagliflozin
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC5
SLC5A1 (SGLT1)
D10669 Sotagliflozin (USAN/INN)
SLC5A2 (SGLT2)
D10669 Sotagliflozin (USAN/INN)
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D10669
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C1y C 14.4200 -16.8000
2 O2x O 14.4200 -15.4000
3 C1y C 13.1600 -14.7000
4 C1y C 11.9700 -15.4000
5 C1y C 11.9700 -16.8000
6 C1y C 13.1600 -17.5000
7 C8x C 21.6300 -19.7400
8 C8y C 22.8200 -19.0400
9 C8x C 22.8200 -17.6400
10 C8x C 21.7000 -16.9400
11 C8y C 20.4400 -17.6400
12 C8x C 20.4400 -18.9700
13 C8y C 18.0600 -18.9700
14 C8y C 18.0600 -17.5700
15 C8x C 16.8700 -16.8000
16 C8y C 15.6100 -17.5000
17 C8x C 15.6100 -18.9000
18 C8x C 16.8000 -19.6700
19 C1b C 19.2500 -16.8700
20 O2a O 24.0800 -19.7400
21 C1b C 25.2700 -19.0400
22 C1a C 26.4600 -19.7400
23 X Cl 19.3200 -19.6700
24 S2a S 13.1600 -13.3000
25 C1a C 14.4200 -12.6000
26 O1a O 10.7800 -14.7000
27 O1a O 10.7800 -17.5000
28 O1a O 13.1600 -18.9000
BOND 30
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 7 8 2
8 8 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 7 12 1
13 13 14 2
14 14 15 1
15 15 16 2
16 16 17 1
17 17 18 2
18 13 18 1
19 14 19 1
20 11 19 1
21 8 20 1
22 20 21 1
23 21 22 1
24 13 23 1
25 1 16 1 #Up
26 3 24 1 #Up
27 24 25 1
28 4 26 1 #Down
29 5 27 1 #Up
30 6 28 1 #Down
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