Homo sapiens (human): 6524
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Entry
6524 CDS
T01001
Symbol
SLC5A2, SGLT2
Name
(RefSeq) solute carrier family 5 member 2
KO
K14382
solute carrier family 5 (sodium/glucose cotransporter), member 2
Organism
hsa
Homo sapiens (human)
Disease
H01126
Familial renal glucosuria
Drug target
Bexagliflozin:
D10865
<US>
Canagliflozin:
D09592
<JP/US>
Dapagliflozin (
DG00122
):
D08897
D09763
<JP/US>
Empagliflozin:
D10459
<JP/US>
Enavogliflozin:
D13015
Ertugliflozin (
DG02836
):
D10313
D11043
<US>
Ipragliflozin (
DG01248
):
D10196
D10200
<JP>
Luseogliflozin:
D10195
<JP>
Remogliflozin etabonate:
D10055
Sergliflozin etabonate:
D06641
Sotagliflozin:
D10669
<US>
Tofogliflozin:
D09978
<JP>
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
6524 (SLC5A2)
04147 Exosome [BR:
hsa04147
]
6524 (SLC5A2)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC5: Sodium glucose cotransporter
6524 (SLC5A2)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
6524 (SLC5A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SSF
Motif
Other DBs
NCBI-GeneID:
6524
NCBI-ProteinID:
NP_003032
OMIM:
182381
HGNC:
11037
Ensembl:
ENSG00000140675
UniProt:
P31639
Structure
PDB
PDBj
LinkDB
All DBs
Position
16:31483123..31490769
Genome browser
AA seq
672 aa
AA seq
DB search
MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGR
SMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNALFVVLLLGWLFAPVYLTA
GVITMPQYLRKRFGGRRIRLYLSVLSLFLYIFTKISVDMFSGAVFIQQALGWNIYASVIA
LLGITMIYTVTGGLAALMYTDTVQTFVILGGACILMGYAFHEVGGYSGLFDKYLGAATSL
TVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWPALLLGLTIVSGWYWCSDQVIVQR
CLAGKSLTHIKAGCILCGYLKLTPMFLMVMPGMISRILYPDEVACVVPEVCRRVCGTEVG
CSNIAYPRLVVKLMPNGLRGLMLAVMLAALMSSLASIFNSSSTLFTMDIYTRLRPRAGDR
ELLLVGRLWVVFIVVVSVAWLPVVQAAQGGQLFDYIQAVSSYLAPPVSAVFVLALFVPRV
NEQGAFWGLIGGLLMGLARLIPEFSFGSGSCVQPSACPAFLCGVHYLYFAIVLFFCSGLL
TLTVSLCTAPIPRKHLHRLVFSLRHSKEEREDLDADEQQGSSLPVQNGCPESAMEMNEPQ
APAPSLFRQCLLWFCGMSRGGVGSPPPLTQEEAAAAARRLEDISEDPSWARVVNLNALLM
MAVAVFLWGFYA
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atggaggagcacacagaggcaggctcggcaccagagatgggggcccagaaggccctgatt
gacaatcctgctgacatcctagtcattgctgcatatttcctgctggtcattggcgttggc
ttgtggtccatgtgcagaaccaacagaggcactgtgggcggctacttcctggcaggacgc
agcatggtgtggtggccggttggggcctctctcttcgccagcaacatcggcagtggccac
tttgtgggcctggcagggactggcgctgcaagtggcttggctgttgctggattcgagtgg
aatgcgctcttcgtggtgctgctactgggctggctgtttgcacccgtgtacctgacagcg
ggggtcatcacgatgccacagtacctgcgcaagcgcttcggcggccgccgcatccgcctc
tacctgtctgtgctctcccttttcctgtacatcttcaccaagatctcagtggacatgttc
tccggagctgtattcatccagcaggctctgggctggaacatctatgcctccgtcatcgcg
cttctgggcatcaccatgatttacacggtgacaggagggctggccgcgctgatgtacacg
gacacggtacagaccttcgtcattctggggggcgcctgcatcctcatgggttacgccttc
cacgaggtgggcgggtattcgggtctcttcgacaaatacctgggagcagcgacttcgctg
acggtgtccgaggatccagccgtgggaaacatctccagcttctgctatcgaccccggccc
gactcctaccacctgctccggcaccccgtgaccggggatctgccgtggcccgcgctgctc
ctcggactcacaatcgtctcgggctggtactggtgcagcgaccaggtcatcgtgcagcgc
tgcctggccgggaagagcctgacccacatcaaggcgggctgcatcctgtgtgggtacctg
aagctgacgcccatgtttctcatggtcatgccaggcatgatcagccgcattctgtaccca
gacgaggtggcgtgcgtggtgcctgaggtgtgcaggcgcgtgtgcggcacggaggtgggc
tgctccaacatcgcctacccgcggctcgtcgtgaagctcatgcccaacggtctgcgcgga
ctcatgctggcggtcatgctggccgcgctcatgtcctcgctggcctccatcttcaacagc
agcagcacgctcttcaccatggacatctacacgcgcctgcggccacgcgccggcgaccgc
gagctgctgctggtgggacggctctgggtggtgttcatcgtggtagtgtcggtggcctgg
cttcccgtggtgcaggcggcacagggcgggcagctcttcgattacatccaggcagtctct
agctacctggcaccgcccgtgtccgccgtcttcgtgctggcgctcttcgtgccgcgcgtt
aatgagcagggcgccttctggggactcatcgggggcctgctgatgggcctggcacgcctg
attcccgagttctccttcggctcgggcagctgtgtgcagccctcggcgtgcccagctttc
ctctgcggcgtgcactacctctacttcgccattgtgctgttcttctgctctggcctcctc
accctcacggtctccctgtgcaccgcgcccatccccagaaagcacctccaccgcctggtc
ttcagtctccggcatagcaaggaggaacgggaggacctggatgctgatgagcagcaaggc
tcctcactccctgtacagaatgggtgcccagagagtgccatggagatgaatgagccccag
gccccggcaccaagcctcttccgccagtgcctgctctggttttgtggaatgagcagaggt
ggggtgggcagtcctccgccccttacccaggaggaggcagcggcagcagccaggcggctg
gaggacatcagcgaggacccgagctgggcccgtgtggtcaacctcaatgccctgctcatg
atggcagtggccgtgttcctctggggcttctatgcctaa
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