KEGG   DRUG: Amifampridine phosphateHelp
Entry
D10689                      Drug                                   

Name
Amifampridine phosphate (USAN);
Firdapse (TN)
Product
Formula
C5H7N3. H3PO4
Exact mass
207.0409
Mol weight
207.1244
Structure
Mol fileKCF fileDB search
Remark
ATC code: N07XX05
Chemical structure group: DG02003
Product (DG02003): D10689<US>
Efficacy
Autoimmune disease treatment, Potassium channel blocker
  Disease
Lambert-Eaton myasthenic syndrome [DS:H01596]
Comment
Treatment of Lambert-Eaton myasthenic syndrome (LEMS)
Target
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX05 Amifampridine
      D10689  Amifampridine phosphate (USAN) <US>
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Potassium channels
    KCNA
     D10689  Amifampridine phosphate (USAN) <US>
    KCNB
     D10689  Amifampridine phosphate (USAN) <US>
    KCNC
     D10689  Amifampridine phosphate (USAN) <US>
    KCND
     D10689  Amifampridine phosphate (USAN) <US>
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D10689
BRITE hierarchy
Other DBs
CAS: 446254-47-3
PubChem: 254741650
ChEMBL: CHEMBL3301611
LinkDB All DBs
KCF data Show

ATOM        13
            1   C8y C    20.3700  -16.7300
            2   C8x C    20.3700  -18.1300
            3   N5x N    21.5600  -18.8300
            4   C8x C    22.8200  -18.1300
            5   C8x C    22.8200  -16.7300
            6   C8y C    21.5600  -16.0300
            7   N1a N    21.5600  -14.6300
            8   N1a N    19.1800  -16.0300
            9   P1b P    26.4600  -17.6400
            10  O1c O    26.4600  -16.2400
            11  O1c O    27.8600  -17.6400
            12  O1c O    25.0600  -17.6400
            13  O1c O    26.4600  -19.0400
BOND        12
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     6   7 1
            8     1   8 1
            9     9  10 2
            10    9  11 1
            11    9  12 1
            12    9  13 1

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